Combined High Resistin and EGFR Expression Predicts a Poor Prognosis in Breast Cancer
المؤلفون المشاركون
Wang, Qian
Huang, Bi-Fei
Zeng, Yue
Shao, Jun-Kang
Jin, Lu-Lu
Tang, Chih-Hsin
Wang, Chao-Qun
Lu, Hua-Jun
Teng, Li-Song
Wang, Yan
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-29
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Elevated levels of resistin and epidermal growth factor receptor (EGFR) facilitate the development of breast cancer, although there are no reports of any correlation between these proteins.
This study analyzed 392 human breast cancer tissue specimens and 42 samples of adjacent normal tissue.
Rates of positive and strongly positive resistin expression were significantly higher in breast cancer tissue than in the adjacent nontumor tissue (83.2% vs.
23.8% and 20.9% vs.
0.0%, respectively; P<0.001 for both comparisons).
Positive resistin expression was significantly associated with tumor size, grade, stage, estrogen receptor (ER), progesterone receptor (PR), human epidermal growth factor receptor 2 (HER2) status, and molecular classification; strongly positive resistin expression was associated with tumor grade, ER, PR, HER2 status, and molecular classification.
Significantly positive correlations were observed between positive and strongly positive resistin expression and corresponding levels of EGFR expression.
Relapse-free and overall survival was worse for patients with high levels of both proteins than for those with high levels of only one protein or normal levels of both proteins.
Our evidence suggests that combined high levels of resistin and EGFR expression correlate with survival in patients with breast cancer.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zeng, Yue& Tang, Chih-Hsin& Wang, Yan& Lu, Hua-Jun& Huang, Bi-Fei& Wang, Qian…[et al.]. 2020. Combined High Resistin and EGFR Expression Predicts a Poor Prognosis in Breast Cancer. BioMed Research International،Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1137723
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zeng, Yue…[et al.]. Combined High Resistin and EGFR Expression Predicts a Poor Prognosis in Breast Cancer. BioMed Research International No. 2020 (2020), pp.1-11.
https://search.emarefa.net/detail/BIM-1137723
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zeng, Yue& Tang, Chih-Hsin& Wang, Yan& Lu, Hua-Jun& Huang, Bi-Fei& Wang, Qian…[et al.]. Combined High Resistin and EGFR Expression Predicts a Poor Prognosis in Breast Cancer. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-11.
https://search.emarefa.net/detail/BIM-1137723
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1137723
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر