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In Vitro Studies on the Degradability, Bioactivity, and Cell Differentiation of PRPAZ31B Mg Alloys Composite Scaffold
المؤلفون المشاركون
Li, Xiaolin
Zou, Jian
Shi, Zhongmin
Xu, Hongwei
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-03-01
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
In recent years, more and more methods have been developed to improve the bioactivity of the biodegradable materials in bone tissue regeneration.
In present study, we used rat mesenchymal stem cells (rMSCs) to evaluate the outcomes of Mg alloys (AZ31B, Magnesium, and Aluminum) and Platelet-rich plasma (PRP)/Mg alloys on rMSCs biocompatibility and osteogenic differentiation.
Water absorption experiments indicated that both bare AZ31B and PRP/AZ31B were capable of absorbing large amounts of water.
But the water absorption ratio for PRP/AZ31B was significantly higher than that for bare AZ31B.
The degradability experiments implied that both samples degraded at same speed.
rMSCs on the surface of AZ31B distributed more and better than those on the AZ31B scaffold.
In ALP activity experiment, the activity of rMSCs on the PRP/AZ31B was markedly higher than that on the AZ31B scaffolds on the 7th day and 14th day.
qRT-PCR also showed that OPN and OCN were expressed in both samples.
OPN and OCN expression in PRP/AZ31B sample were higher than those in bare AZ31B samples.
In summary, the in vitro study implied that AZ31B combined with PRP could remarkably improve cell seeding, attachment, proliferation, and differentiation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zou, Jian& Shi, Zhongmin& Xu, Hongwei& Li, Xiaolin. 2017. In Vitro Studies on the Degradability, Bioactivity, and Cell Differentiation of PRPAZ31B Mg Alloys Composite Scaffold. BioMed Research International،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1137753
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zou, Jian…[et al.]. In Vitro Studies on the Degradability, Bioactivity, and Cell Differentiation of PRPAZ31B Mg Alloys Composite Scaffold. BioMed Research International No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1137753
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zou, Jian& Shi, Zhongmin& Xu, Hongwei& Li, Xiaolin. In Vitro Studies on the Degradability, Bioactivity, and Cell Differentiation of PRPAZ31B Mg Alloys Composite Scaffold. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1137753
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1137753
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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