Correlation between Skip N2 Metastases and SUVmax, Long Diameter of Tumor, and Ki67 Expression in Patients with Non-Small-Cell Lung Cancer
المؤلفون المشاركون
Shao, Guoqiang
Jian, Wang
Ming-ya, Peng
Long-bao, Xu
Jun, Zhao
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-04-27
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
We aim at investigating the correlation between skip N2 metastases (SN2) and SUVmax, long diameter of tumor mass after 18F-FDG PET/CT, and pathological Ki67 expression in patients with non-small-cell lung cancer (NSCLC).
Methods and Results.
We retrospectively analyzed the factors that might affect the pathogenesis of SN2 in these patients.
The clinical SN2 symptoms in patients with squamous carcinoma or adenocarcinoma were investigated.
The work curve was utilized to analyze the optimal cutoff value for the SUVmax and long diameter of tumor.
Multivariate analysis revealed that high expression of Ki67 was a risk factor for mediastinal SN2 (OR=1.042, 95% CI: 1.009-1.076).
Subgroup analysis indicated that the SUVmax of the non-SN2 group was significantly higher than that of the SN2 group in patients with squamous carcinoma (16.3±6.0 vs.
10.7±5.6, P=0.026).
In the patients with adenocarcinoma, the long diameter of tumor in the SN2 group was significantly longer than that of the non-SN2 group (43.8±16.3 mm vs.
30.1±13.8 mm, P=0.032).
The Ki67 expression in the SN2 group was significantly higher than that of the non-SN2 group (51.7±24.0 vs.
30.0±19.2, P=0.028).
Conclusions.
The differences of clinical features of the patients in the SN2 group and non-SN2 group in the NSCLC patients were associated with the pathological subtypes, which were featured by lower SUVmax in the SN2 of the squamous carcinoma, and longer diameter of SN2 in the adenocarcinoma patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jian, Wang& Ming-ya, Peng& Long-bao, Xu& Jun, Zhao& Shao, Guoqiang. 2020. Correlation between Skip N2 Metastases and SUVmax, Long Diameter of Tumor, and Ki67 Expression in Patients with Non-Small-Cell Lung Cancer. BioMed Research International،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1138057
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jian, Wang…[et al.]. Correlation between Skip N2 Metastases and SUVmax, Long Diameter of Tumor, and Ki67 Expression in Patients with Non-Small-Cell Lung Cancer. BioMed Research International No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1138057
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jian, Wang& Ming-ya, Peng& Long-bao, Xu& Jun, Zhao& Shao, Guoqiang. Correlation between Skip N2 Metastases and SUVmax, Long Diameter of Tumor, and Ki67 Expression in Patients with Non-Small-Cell Lung Cancer. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1138057
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1138057
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر