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Incidence of Infection of Enterovirus 71 and Coxsackieviruses A6 and A16 among Household Contacts of Index Cases in Dong Thap Province, Southern Vietnam
المؤلفون المشاركون
Hoang, C. Q.
Nguyen, H. D.
Ho, N. X.
Vu, T. H. T.
Pham, T. T. M.
Nguyen, K. T.
Hoang, L. T.
Clapham, H.
Nguyen, T. T. T.
Phan, L. T.
Nguyen, H. T.
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-11-20
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Background.
Scarce information exists about immunity to hand, foot, and mouth disease (HFMD) among household contacts of index cases in Vietnam and what that means for reducing ongoing HFMD transmission in the community.
Methods.
We analyzed neutralizing antibodies (NT) and the incidence of enterovirus (EVs) infection among household contacts of index cases in a province where HFMD remains endemic.
Throat swab and 2 mL blood samples from household contacts were collected at enrollment, during and after 2 weeks follow-up.
Results.
The incidence of EV-A71 infection among household contacts was 40/84 (47.6%, 95% Cl: 36.9-58.3%), compared with 106/336 (31.5%, 95% Cl: 26.6-36.5%) for CV-A6 and 36/107 (33.6%, 95% Cl: 24.7-42.6%) for CV-A16.
The incidence of CV-A6 infection was fairly constant across ages; in contrast, CV-A71 and CV-A16 had some variation across ages.
At baseline, higher geometric mean titer (GMT) of EV-A71, CV-A6, and CV-A16 antibody titers was found for 25-34-year groups (range 216.3 to 305.0) compared to the other age groups.
There was a statistically significant difference in GMT values of CV-A6 and CV-A16 between those who had an infection or did not have infection among households with an index case of these serotypes.
Conclusions.
Our results indicated that adults were becoming infected with HFMD and could be contributing to the transmission.
There is, therefore, a need for considering the household setting as an additional target for intervention programs for HFMD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hoang, C. Q.& Nguyen, H. D.& Ho, N. X.& Vu, T. H. T.& Pham, T. T. M.& Nguyen, K. T.…[et al.]. 2020. Incidence of Infection of Enterovirus 71 and Coxsackieviruses A6 and A16 among Household Contacts of Index Cases in Dong Thap Province, Southern Vietnam. BioMed Research International،Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1138328
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hoang, C. Q.…[et al.]. Incidence of Infection of Enterovirus 71 and Coxsackieviruses A6 and A16 among Household Contacts of Index Cases in Dong Thap Province, Southern Vietnam. BioMed Research International No. 2020 (2020), pp.1-8.
https://search.emarefa.net/detail/BIM-1138328
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hoang, C. Q.& Nguyen, H. D.& Ho, N. X.& Vu, T. H. T.& Pham, T. T. M.& Nguyen, K. T.…[et al.]. Incidence of Infection of Enterovirus 71 and Coxsackieviruses A6 and A16 among Household Contacts of Index Cases in Dong Thap Province, Southern Vietnam. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-8.
https://search.emarefa.net/detail/BIM-1138328
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1138328
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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