Unilateral Multifocality and Bilaterality Could Be Two Different Multifocal Entities in Patients with Papillary Thyroid Microcarcinoma
المؤلفون المشاركون
Cai, Junbo
Fang, Fang
Chen, Jianbin
Xiang, Dapeng
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-07-04
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
Multifocality within an affected lobe (unilateral multifocality) or two lobes (bilaterality) is commonly denoted as multifocality without differentiation.
Recently, there has been molecular evidence indicating that unilateral multifocality and bilaterality could be two different entities.
However, few studies concerning the comparison between these two different multifocality entities have been reported.
Design.
A retrospective cohort study.
Methods.
From 2010 to 2013, in total, 949 consecutive patients with papillary thyroid microcarcinoma (PTMC) were enrolled and further divided into four groups based on multifocality status.
Unilateral multifocality and bilaterality were analyzed by binary logistic regression along with other clinicopathological factors.
Results.
Unilateral multifocality, instead of bilaterality, was correlated with central neck metastasis (CNM) in both univariate and multivariate analyses.
Group IV (unilateral multifocality and bilaterality coexist) had the highest CNM rate.
Group III (unilateral multifocality) had a higher CNM rate than group II (bilaterality, single lesion in each lobe), with a significant difference (p=0.032).
Similar lateral neck metastasis tendency was observed among the four groups.
In the multivariate analysis, only unilateral multifocality and bilaterality which coexisted were correlated with CNM.
Moreover, 9 cases had a recurrence, with the recurrence rate ranking top in group IV (3.6%), second in group III (2.8%), and third in group II (1.2%).
The difference was significant (p=0.021).
Conclusion.
Unilateral multifocality and bilaterality could be two different multifocal entities in patients with PTMC.
Unilateral multifocality serving as a prognostic factor indicated a worse prognosis than bilaterality on neck metastasis.
When the two factors coexisted in PTMC, patients had the highest risk of CNM and possibly local recurrence compared with those with either risk factor alone.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cai, Junbo& Fang, Fang& Chen, Jianbin& Xiang, Dapeng. 2020. Unilateral Multifocality and Bilaterality Could Be Two Different Multifocal Entities in Patients with Papillary Thyroid Microcarcinoma. BioMed Research International،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1138330
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cai, Junbo…[et al.]. Unilateral Multifocality and Bilaterality Could Be Two Different Multifocal Entities in Patients with Papillary Thyroid Microcarcinoma. BioMed Research International No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1138330
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cai, Junbo& Fang, Fang& Chen, Jianbin& Xiang, Dapeng. Unilateral Multifocality and Bilaterality Could Be Two Different Multifocal Entities in Patients with Papillary Thyroid Microcarcinoma. BioMed Research International. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1138330
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1138330
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر