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Ultrasound Mediated Microbubbles Destruction Augmented Sonolysis: An In Vitro and In Vivo Study
المؤلفون المشاركون
Tan, Kaibin
Xia, Hongmei
Liu, Zheng
Xu, Yali
Zhu, Qiong
Gao, Yunhua
Cui, Hai
He, Ying
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-16
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Objective.
This study was aimed at exploring ultrasound mediated microbubbles destruction (UMMD) assisted sonolysis in both the in vitro and in vivo clots.
Methods.
Therapeutic ultrasound (TUS) and lipid microbubbles (MBs) were used in whole blood clots and divided into the control, TUS group, and TUS + MB group.
Thrombolytic rates and microscopy were performed.
Color Doppler flow imaging (CDFI) and angiography were performed to evaluate the recanalization rates and flow scores in femoral arterial thrombus (FAT) in rabbits.
FAT were dyed with H&E.
Results.
The average thrombolytic ratios of TUS + MB group were significantly higher than those of TUS group and the control group (both P<0.05).
Clots had different pathological changes.
Recanalization rates and flow scores in TUS + MB group were significantly higher than the control and TUS group.
Flow scores and recanalization ratios were grade 0 in 0% of the control group, grade I in 25% of TUS group, and grade II or higher in 87.5% of TUS + MB group after 30 min sonolysis.
Conclusions.
Both the in vitro and in vivo sonolysis can be significantly augmented by the introduction of MBs without thrombolytic agents, which might be induced by the enhanced cavitation via UMMD.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cui, Hai& Zhu, Qiong& Gao, Yunhua& Xia, Hongmei& Tan, Kaibin& He, Ying…[et al.]. 2017. Ultrasound Mediated Microbubbles Destruction Augmented Sonolysis: An In Vitro and In Vivo Study. BioMed Research International،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1138332
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cui, Hai…[et al.]. Ultrasound Mediated Microbubbles Destruction Augmented Sonolysis: An In Vitro and In Vivo Study. BioMed Research International No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1138332
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cui, Hai& Zhu, Qiong& Gao, Yunhua& Xia, Hongmei& Tan, Kaibin& He, Ying…[et al.]. Ultrasound Mediated Microbubbles Destruction Augmented Sonolysis: An In Vitro and In Vivo Study. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1138332
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1138332
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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