Neuropsychological and Emotional Functioning in Patients with Cushing’s Syndrome
المؤلفون المشاركون
Na, Sabrina
Fernandes, Mary A.
Ioachimescu, Adriana G.
Penna, Suzanne
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-08-07
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Patients with Cushing’s syndrome (CS) frequently report impairments in cognitive and emotional functioning.
Given neuroimaging research that implicates alterations in structure and function in the brain in this population, goals of this study were to investigate neuropsychological and emotional functioning, with particular emphasis on complex attention and memory.
In a clinical sample of 18 adults with CS referred for neuropsychological evaluation (age 41.6±10.6, 72% Caucasian), patients’ most common subjective complaints were in attention and increased irritability.
On objective testing, patients exhibited significant declines in the consistency of their sustained attention and visual-spatial functioning compared to normative peers.
Patients exhibited on average significantly reduced initial learning following first exposure to visual and verbal stimuli but intact retention of information learned.
Patients with CS endorsed highly elevated levels of somatization, depression, and anxiety, and 59% of them scored in the clinically elevated range for somatization and depressive symptomatology.
Exploratory analyses suggested that the 11 patients with active Cushing’s exhibited lower processing speed, poorer sustained attention, naming, and cognitive flexibility compared to the 7 patients who achieved biochemical remission.
Patients with active Cushing’s also reported higher levels of somatization and anxiety compared to patients in biochemical remission.
Overall, this study provides new insights into complex attention and memory deficits in patients with CS and concern regarding cognitive and emotional issues despite resolution of hypercortisolism.
Our study opens several avenues for further exploration.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Na, Sabrina& Fernandes, Mary A.& Ioachimescu, Adriana G.& Penna, Suzanne. 2020. Neuropsychological and Emotional Functioning in Patients with Cushing’s Syndrome. Behavioural Neurology،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1138383
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Na, Sabrina…[et al.]. Neuropsychological and Emotional Functioning in Patients with Cushing’s Syndrome. Behavioural Neurology No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1138383
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Na, Sabrina& Fernandes, Mary A.& Ioachimescu, Adriana G.& Penna, Suzanne. Neuropsychological and Emotional Functioning in Patients with Cushing’s Syndrome. Behavioural Neurology. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1138383
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1138383
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر