Small Fiber Neuropathy: Clinicopathological Correlations
المؤلفون المشاركون
Pál, Endre
Janszky, József
Komoly, Sámuel
Fülöp, Krisztina
Tóth, Péter
Deli, Gabriella
Pfund, Zoltán
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-01-02
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Small fiber neuropathy develops due to the selective damage of the thin fibers of peripheral nerves.
Many common diseases can cause this condition, including diabetes, infections, autoimmune and endocrine disorders, but it can occur due to genetic alterations, as well.
Eighty-five skin biopsy-proven small-fiber neuropathy cases were analyzed.
Forty-one (48%) cases were idiopathic; among secondary types, hypothyreosis (9.4%), diabetes mellitus (7%), cryoglobulinemia (7%), monoclonal gammopathy with unproved significance (4.7%), Sjögren’s disease (3%), and paraneoplastic neuropathy (3%) were the most common causes.
Two-thirds (68%) of the patients were female, and the secondary type started 8 years later than the idiopathic one.
In a vast majority of the cases (85%), the distribution followed a length-dependent pattern.
Intraepidermal fiber density was comparable in idiopathic and secondary forms.
Of note, we found significantly more severe pathology in men and in diabetes.
Weak correlation was found between patient-reported measures and pathology, as well as with neuropathic pain-related scores.
Our study confirmed the significance of small fiber damage-caused neuropathic symptoms in many clinical conditions, the gender differences in clinical settings, and pathological alterations, as well as the presence of severe small fiber pathology in diabetes mellitus, one of the most common causes of peripheral neuropathy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pál, Endre& Fülöp, Krisztina& Tóth, Péter& Deli, Gabriella& Pfund, Zoltán& Janszky, József…[et al.]. 2020. Small Fiber Neuropathy: Clinicopathological Correlations. Behavioural Neurology،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1138424
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pál, Endre…[et al.]. Small Fiber Neuropathy: Clinicopathological Correlations. Behavioural Neurology No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1138424
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pál, Endre& Fülöp, Krisztina& Tóth, Péter& Deli, Gabriella& Pfund, Zoltán& Janszky, József…[et al.]. Small Fiber Neuropathy: Clinicopathological Correlations. Behavioural Neurology. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1138424
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1138424
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر