Discharge Hemoglobin Association with Long-Term Outcomes of ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention
المؤلفون المشاركون
Zhang, Zhiguo
Gao, Ming
Zhang, Xinying
Qin, Ling
Zheng, Yang
Tong, Qian
Li, Hang
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-03-01
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Anemia following acute myocardial infarction (AMI) is associated with poor outcomes.
While previous studies in patients with AMI have focused on anemia at admission, we hypothesized that hemoglobin (Hb) decline during hospitalization and lower discharge Hb would be associated with greater long-term mortality in patients undergoing primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI).
Methods.
We analyzed records of 983 STEMI patients who were treated with primary PCI.
The primary end point was all-cause mortality at 1 year and 2 years.
The relationship between discharge Hb levels, decline in Hb levels, bleeding event classification, and all-cause mortality was determined.
Results.
Overall, 16.4% of patients had bleeding events, which were classified by the Thrombolysis in Myocardial Infarction (TIMI) score as 7% minimal, 8.6% minor, and 0.9% major.
No significant gastrointestinal bleed and cerebral hemorrhage occurred in hospitals among these patients.
The incidence rate of the 2-year all-cause mortality increased with severity of the bleeding event score (8.78% for no bleeding vs.
11.59% for minimal bleeding vs.
20.24% for minor bleeding vs.
55.56% for major bleeding, P<0.001).
Discharge Hb was significantly associated with 2-year mortality in an unadjusted model (hazard ratio (HR) per 1 g/L decrease in discharge Hb = 1.020, 95% confidence interval (CI): 1.006–1.034, P=0.004) and in a confounder-adjusted model (HR per 1 g/L decrease in discharge Hb = 1.024, 95% CI: 1.011–1.037, P<0.001).
The odds ratio (OR) for all-cause mortality at 2 years for participants with Hb below the twentieth percentile was 3.529 (95% CI: 1.976–6.302) and 2.968 (95% CI: 1.614–5.456) after adjustment for age and gender and 2.485 (95% CI: 1.310–4.715) after adjustment for all covariates.
Conclusions.
In this population of patients hospitalized for STEMI, all-cause mortality increased with lower discharge Hb, and discharge Hb was a significant predictor of mortality risk.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gao, Ming& Zhang, Xinying& Qin, Ling& Zheng, Yang& Zhang, Zhiguo& Tong, Qian…[et al.]. 2020. Discharge Hemoglobin Association with Long-Term Outcomes of ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention. Cardiovascular Therapeutics،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1138640
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gao, Ming…[et al.]. Discharge Hemoglobin Association with Long-Term Outcomes of ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention. Cardiovascular Therapeutics No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1138640
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gao, Ming& Zhang, Xinying& Qin, Ling& Zheng, Yang& Zhang, Zhiguo& Tong, Qian…[et al.]. Discharge Hemoglobin Association with Long-Term Outcomes of ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention. Cardiovascular Therapeutics. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1138640
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1138640
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر