Role of Terlipressin in Cirrhotic Patients with Ascites and without Hepatorenal Syndrome: A Systematic Review of Current Evidence
المؤلفون المشاركون
Méndez-Sánchez, Nahum
Teschke, Rolf
Guo, Xiaozhong
Bai, Zhaohui
An, Yang
Li, Hongyu
Qi, Xingshun
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-06-24
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Ascites, a common complication in cirrhosis, is prone to the development of acute kidney injury or hepatorenal syndrome and can be complicated by circulatory dysfunction after paracentesis.
Terlipressin has not been considered as the mainstay treatment option for ascites in cirrhosis yet.
The present work aimed to systematically review the current evidence regarding the use of terlipressin in cirrhosis with ascites and without hepatorenal syndrome.
PubMed, EMBASE, and Cochrane Library databases were searched for relevant studies.
Twelve studies were eligible.
In 3 studies (1 randomized controlled trial and 2 single-arm studies without controls) involving 32 patients who received terlipressin for nonrefractory ascites, terlipressin improved hemodynamics by decreasing the heart rate and cardiac output and increasing the mean arterial pressure and systemic vascular resistance.
In 5 studies (1 randomized controlled trial, 2 single-arm studies without controls, and 2 comparative studies with controls) involving 67 patients who received terlipressin for refractory ascites, terlipressin improved renal function by increasing the glomerular filtration rate, renal blood flow, urinary sodium, and urine output and decreasing serum creatinine.
In 4 studies (4 randomized controlled trials) involving 71 patients who received terlipressin for preventing from paracentesis-induced circulatory dysfunction, terlipressin prevented from paracentesis-induced circulatory dysfunction by increasing the mean arterial pressure and systemic vascular resistance and decreasing plasma renin.
Terlipressin may improve hemodynamics, severity of ascites, and renal function and prevent from paracentesis-induced circulatory dysfunction in cirrhosis with ascites and without hepatorenal syndrome.
However, no study has evaluated the effect of terlipressin for prevention of acute kidney injury.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Bai, Zhaohui& An, Yang& Guo, Xiaozhong& Teschke, Rolf& Méndez-Sánchez, Nahum& Li, Hongyu…[et al.]. 2020. Role of Terlipressin in Cirrhotic Patients with Ascites and without Hepatorenal Syndrome: A Systematic Review of Current Evidence. Canadian Journal of Gastroenterology and Hepatology،Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1139015
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Bai, Zhaohui…[et al.]. Role of Terlipressin in Cirrhotic Patients with Ascites and without Hepatorenal Syndrome: A Systematic Review of Current Evidence. Canadian Journal of Gastroenterology and Hepatology No. 2020 (2020), pp.1-7.
https://search.emarefa.net/detail/BIM-1139015
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Bai, Zhaohui& An, Yang& Guo, Xiaozhong& Teschke, Rolf& Méndez-Sánchez, Nahum& Li, Hongyu…[et al.]. Role of Terlipressin in Cirrhotic Patients with Ascites and without Hepatorenal Syndrome: A Systematic Review of Current Evidence. Canadian Journal of Gastroenterology and Hepatology. 2020. Vol. 2020, no. 2020, pp.1-7.
https://search.emarefa.net/detail/BIM-1139015
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139015
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر