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Regulating Intestinal Microbiota in the Prevention and Treatment of Alcohol-Related Liver Disease
المؤلفون المشاركون
Chi, Xin
Pan, Calvin Q.
Liu, Shunai
Cheng, Danying
Cao, Ziwen
Xing, Huichun
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-12-17
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
When alcohol-related liver disease occurs, the number and composition ratio of intestinal microorganisms will accordingly change.
The alcohol-induced changes in the intestinal microbiota play a pivotal role in the process of developing the alcohol-related liver disease through the translocation of microbial products due to increased intestinal permeability.
In recent years, therapeutic interventions with a concentration on regulating intestinal microbiota have been conducted for patients with alcohol-related liver disease.
We aimed to provide a critical review and updates on the prevention and treatment of alcohol-related liver disease through regulating intestinal microbiota.
A literature search was performed on the PubMed database for studies published in English about the therapeutic intervention with microbiota using animal models and patients with alcohol-related liver disease (1/2010–4/2020).
The accumulating pieces of evidence suggest that the therapeutic use of probiotics, prebiotics, antibiotics, phages, or fecal microbial transplantation may have several influences on alcohol-related liver disease patients.
Emergent data unveiled that these interventions can further regulate the composition of intestinal microbiota, minimize the negative impact of microbiota on the liver, and prevent disease progression from mild to severe alcoholic hepatitis, fibrosis, cirrhosis, or even liver cancer.
The current review provides updates on the advances of therapeutic interventions with the effects of regulating intestinal microbiota on patients who have alcohol-related liver disease.
In addition, the data gaps and research directions on further exploration of the role of intestinal microbiota for the management of the alcohol-related liver disease are also discussed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chi, Xin& Pan, Calvin Q.& Liu, Shunai& Cheng, Danying& Cao, Ziwen& Xing, Huichun. 2020. Regulating Intestinal Microbiota in the Prevention and Treatment of Alcohol-Related Liver Disease. Canadian Journal of Gastroenterology and Hepatology،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1139022
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chi, Xin…[et al.]. Regulating Intestinal Microbiota in the Prevention and Treatment of Alcohol-Related Liver Disease. Canadian Journal of Gastroenterology and Hepatology No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1139022
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chi, Xin& Pan, Calvin Q.& Liu, Shunai& Cheng, Danying& Cao, Ziwen& Xing, Huichun. Regulating Intestinal Microbiota in the Prevention and Treatment of Alcohol-Related Liver Disease. Canadian Journal of Gastroenterology and Hepatology. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1139022
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139022
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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