Prevalence of Hepatitis C Virus Infection in a Surgical Population of Southeast China: A Large-Scale Multicenter Study
المؤلفون المشاركون
Zou, Pengfei
Chen, Yongping
Liu, Jimin
Li, Lanjuan
Zheng, Yang
Cai, Yubo
Peng, Conggao
Tong, Zhaowei
Li, Nan
Chen, Ping
Gao, Hainv
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-04-15
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background.
Chronic HCV infection affects 80 million people globally and may progress to advanced liver disease.
The present study aims to investigate the present epidemiology of HCV infection in a southeastern Chinese surgical patient cohort.
Methods.
Blood samples obtained from 78,484 surgical patients from 18 different city and county hospitals were enrolled.
The incidence of serum HCV antibody positivity, HCV RNA load, and HCV genotyping, as well as demographics and relevant clinical history, were investigated.
Data were stratified using the multistage cluster random sampling method and further analyzed using the SPSS-20 package.
Results.
HCV antibody positivity was detected in 0.15% of the population (95% confidence interval (CI): 0.12%–0.18%).
Genotype 1b (55.74%) was the dominant type.
The HCV infection peaked in the age groups of 16–20, 41–50, and 61–65 years, and it was higher in males than in females (0.19% vs.
0.13%, P<0.05).
The geographical distribution of infection rates differed: 0.19% (95% CI: 0.14%–0.24%), 0.18% (95% CI: 0.13%–0.23%), and 0.06% (95% CI: 0.03–0.09%) in plain areas, islands, and valley regions, respectively.
Patients with transfusion history and urban residence were associated with high HCV RNA levels (adjusted odds ratio = 11.24 and 6.20, P<0.05).
Conclusion.
The prevalence of HCV infection in this cohort from southeast China was 0.17%, which is lower than the reported 0.43% infection rate in China in 2006.
This result can be (partially) explained by the improvement of blood donor screening and the successful campaign for the use of disposable syringes and needles.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Chen, Ping& Zheng, Yang& Cai, Yubo& Zou, Pengfei& Li, Nan& Peng, Conggao…[et al.]. 2020. Prevalence of Hepatitis C Virus Infection in a Surgical Population of Southeast China: A Large-Scale Multicenter Study. Canadian Journal of Gastroenterology and Hepatology،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1139037
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Chen, Ping…[et al.]. Prevalence of Hepatitis C Virus Infection in a Surgical Population of Southeast China: A Large-Scale Multicenter Study. Canadian Journal of Gastroenterology and Hepatology No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1139037
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Chen, Ping& Zheng, Yang& Cai, Yubo& Zou, Pengfei& Li, Nan& Peng, Conggao…[et al.]. Prevalence of Hepatitis C Virus Infection in a Surgical Population of Southeast China: A Large-Scale Multicenter Study. Canadian Journal of Gastroenterology and Hepatology. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1139037
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139037
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر