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Splenectomy with Portoazygous Disconnection for Correction of Systemic Hemodynamic Disorders in Hepatic Cirrhosis Patients with Portal Hypertension: A Prospective Single-Center Cohort Study
المؤلفون المشاركون
Lu, Shi-Chun
Ding, Jing
Zhao, Xiao-Fei
Zeng, Dao-Bing
Di, Liang
Guo, Qing-Liang
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-12-21
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
To investigate the effect of splenectomy for correction of systemic hemodynamic disorders in hepatic cirrhosis patients with portal hypertension.
Methods.
Hepatic cirrhosis patients with portal hypertension were enrolled from April 2015 to July 2018.
Systemic hemodynamic parameters (heart rate, mean arterial pressure (MAP), cardiac output, and total peripheral vascular resistance (TPR)) were prospectively measured at baseline and 1 week, 1, 3, and 6 months, and 1, 2, and 3 years postoperatively.
Paired analysis was conducted.
Results.
Sixty-nine patients were eligible, and 55 (79.7%) cases had a history of upper gastrointestinal bleeding.
Child–Pugh classification was grade A in 41 (59.4%) cases, grade B in 26 (37.7%) cases, and grade C in 2 (2.9%) cases.
The heart rate was significantly higher at 1 week postoperatively versus the baseline (P<0.001).
Meanwhile, the heart rate was significantly lower from 3 months to 2 years postoperatively versus the baseline (P<0.05).
The MAP was significantly higher at 6 months to 2 years postoperatively versus the baseline (P<0.05).
At 1 month postoperatively and 6 months to 2 years, the cardiac output was significantly lower versus the baseline (P<0.05).
At 1 month postoperatively and 6 months to 2 years, the TPR was significantly higher versus the baseline (P<0.05).
Conclusion.
Splenectomy corrects systemic hemodynamic disorder in hepatic cirrhosis patients with portal hypertension, and the effect is rapid and durable.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zeng, Dao-Bing& Di, Liang& Guo, Qing-Liang& Ding, Jing& Zhao, Xiao-Fei& Lu, Shi-Chun. 2020. Splenectomy with Portoazygous Disconnection for Correction of Systemic Hemodynamic Disorders in Hepatic Cirrhosis Patients with Portal Hypertension: A Prospective Single-Center Cohort Study. Canadian Journal of Gastroenterology and Hepatology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1139077
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zeng, Dao-Bing…[et al.]. Splenectomy with Portoazygous Disconnection for Correction of Systemic Hemodynamic Disorders in Hepatic Cirrhosis Patients with Portal Hypertension: A Prospective Single-Center Cohort Study. Canadian Journal of Gastroenterology and Hepatology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1139077
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zeng, Dao-Bing& Di, Liang& Guo, Qing-Liang& Ding, Jing& Zhao, Xiao-Fei& Lu, Shi-Chun. Splenectomy with Portoazygous Disconnection for Correction of Systemic Hemodynamic Disorders in Hepatic Cirrhosis Patients with Portal Hypertension: A Prospective Single-Center Cohort Study. Canadian Journal of Gastroenterology and Hepatology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1139077
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139077
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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