Prevalence and Molecular Genetics of Methicillin-Resistant Staphylococcus aureus Colonization in Nursing Homes in Saudi Arabia
المؤلفون المشاركون
Albarrag, Ahmed
Shami, Ashwag
Almutairi, Abrar
Alsudairi, Sara
Aldakeel, Sumayh
Al-Amodi, Amani
المصدر
Canadian Journal of Infectious Diseases and Medical Microbiology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-06-03
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Objective.
Methicillin-resistant Staphylococcus aureus (MRSA) is one of the main causative agents of nosocomial infections that has posed a major threat to those with compromised immune systems such as nursing home residents.
The aim of this study was to determine the rates of MRSA strains and the types of Staphylococcal Cassette Chromosome mec (SCCmec)in nursing homes in Saudi Arabia.
Methods.
A total of 188 nasal swabs were collected from the residents and nursing staff in two nursing homes in Riyadh, Saudi Arabia.
All MRSA isolates were tested for antimicrobial susceptibility and analyzed for mecA and SCCmec typing by multiplex PCR assay.
Detection of the Panton–Valentine leukocidin (PVL) gene was also tested in all positive MRSA isolates by multiplex PCR using specific primers.
Results.
Among the 188 collected nasal swabs (105 males and 83 females), MRSA colonization rate was 9.04% (11 (5.85%) females and 6 (5.71%) males).
About 47% of MRSA were multidrug resistant (MDR) as acquired resistance to beta-lactam, macrolide, and aminoglycoside antibiotics.
However, all the MRSA isolates showed susceptibility to vancomycin, tigecycline, and linezolid.
All the MRSA isolates (n = 17) were mecA-positive with the SCCmec IVc (n = 7, 41.18%) as the most common SCCmec type followed by SCCmec V (n = 5, 29.41%) and SCCmec IVa (n = 2, 11.76%).
The remaining isolates (n = 3) were nontypeable (17.65%).
In addition, the PVL toxin gene was only detected in four of the male samples.
Conclusion.
MRSA nasal colonization is a common incident among nursing home residents.
The prevalence of community-associated (CA) MRSA (SCCmec IV and V) was more common than hospital-associated (HA) MRSA in our study samples.
It is crucial to investigate such rate of incidence, which is a key tool in preventive medicine and would aid in determining health policy and predict emergent outbreaks.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Albarrag, Ahmed& Shami, Ashwag& Almutairi, Abrar& Alsudairi, Sara& Aldakeel, Sumayh& Al-Amodi, Amani. 2020. Prevalence and Molecular Genetics of Methicillin-Resistant Staphylococcus aureus Colonization in Nursing Homes in Saudi Arabia. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1139113
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Albarrag, Ahmed…[et al.]. Prevalence and Molecular Genetics of Methicillin-Resistant Staphylococcus aureus Colonization in Nursing Homes in Saudi Arabia. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1139113
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Albarrag, Ahmed& Shami, Ashwag& Almutairi, Abrar& Alsudairi, Sara& Aldakeel, Sumayh& Al-Amodi, Amani. Prevalence and Molecular Genetics of Methicillin-Resistant Staphylococcus aureus Colonization in Nursing Homes in Saudi Arabia. Canadian Journal of Infectious Diseases and Medical Microbiology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1139113
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139113
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر