Clinical and Pathogenic Characteristics of Lower Respiratory Tract Infection Treated at the Vietnam National Children’s Hospital
المؤلفون المشاركون
Pham, Hien T.
Nguyen, Phuc T. T.
Tran, Sinh T.
Phung, Thuy T. B.
المصدر
Canadian Journal of Infectious Diseases and Medical Microbiology
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-03-11
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Lower respiratory tract infections are commonly caused by viruses and cause significant morbidity and mortality among children.
Early identification of the pathological agent causing these infections is essential to avoid unnecessary antibiotic use and improve patient management.
Multiplex PCR techniques were recently developed to detect multiple viral pathogens using a single PCR reaction.
In this study, we identify viral pathogens in children with respiratory infections.
We collected 194 nasopharyngeal aspirates from infants (2–24 months old) with lower respiratory tract infections treated at the Vietnam National Children’s Hospital between November 2014 and June 2015 and assessed the presence of 16 virus types and subtypes by multiplex PCR using the xTAG Respiratory Viral Panel (RVP) assay.
Overall, 73.7% of the samples were positive for at least one virus, and 24.2% corresponded to infections with multiple viruses.
The most common viruses were respiratory syncytial virus and enterovirus/rhinovirus.
These viruses were more frequent among younger patients (2–5 months old) and caused symptoms similar to those of bronchiolitis and pneumonia.
The most common clinical manifestation caused by respiratory tract infection was bronchiolitis.
Elevated neutrophils levels were associated with adenovirus infection.
Our results showed that the xTAG Respiratory Viral Panel (RVP) can effectively detect multiple viruses causing respiratory infections in children and that the nasopharyngeal aspirates are a good sample choice to detect respiratory viruses in children.
Applying this approach in the clinical setting would improve patient management and allow early diagnosis, thus avoiding the unnecessary use of antibiotics.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Pham, Hien T.& Nguyen, Phuc T. T.& Tran, Sinh T.& Phung, Thuy T. B.. 2020. Clinical and Pathogenic Characteristics of Lower Respiratory Tract Infection Treated at the Vietnam National Children’s Hospital. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1139179
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Pham, Hien T.…[et al.]. Clinical and Pathogenic Characteristics of Lower Respiratory Tract Infection Treated at the Vietnam National Children’s Hospital. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1139179
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Pham, Hien T.& Nguyen, Phuc T. T.& Tran, Sinh T.& Phung, Thuy T. B.. Clinical and Pathogenic Characteristics of Lower Respiratory Tract Infection Treated at the Vietnam National Children’s Hospital. Canadian Journal of Infectious Diseases and Medical Microbiology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1139179
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139179
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر