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Molecular Magnetic Resonance Imaging with Contrast Agents for Assessment of Inflammatory Bowel Disease: A Systematic Review
المؤلفون المشاركون
Luo, Yifan
Gao, Chen
Chen, Wujie
Zhou, Kefeng
Xu, Maosheng
المصدر
Contrast Media & Molecular Imaging
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-05-06
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Background and Aims.
Magnetic resonance imaging (MRI) has taken an important role in the diagnosis of inflammatory bowel diseases (IBD).
In the wake of current advances in nanotechnology, the drug delivery industry has seen a surge of nanoparticles advertising high specificity in target imaging.
Given the rapid development of the field, this review has assembled related articles to explore whether molecular contrast agents can improve the diagnostic capability on gastrointestinal imaging, especially for IBD.
Methods.
Relevant articles published between 1998 and 2018 from a literature search of PubMed and EMBASE were reviewed.
Data extraction was performed on the studies’ characteristics, experimental animals, modelling methods, nanoparticles type, magnetic resonance methods, and means of quantitative analysis.
Results.
A total of 8 studies were identified wherein the subjects were animals, and all studies employed MR equipment.
One group utilized a perfluorocarbon solution and the other 7 groups used either magnetic nanoparticles or gadolinium- (Gd-) related nanoparticles for molecular contrast.
With ultrasmall superparamagnetic iron oxide (USPIO) particles and Gd-related nanoparticles, signal enhancements were found in the mucosa or with focal lesion of IBD-related model in T1-weighted images (T1WI), whereas superparamagnetic iron oxide (SPIO) particles showed a signal decrease in the intestinal wall of the model in T1WI or T2-weighted images.
The signal-to-noise ratio (SNR) was employed to analyze bowel intensity in 3 studies.
And the percentage of normalized enhancement was used in 1 study for assessing the severity of inflammation.
Conclusion.
Molecular MRI with contrast agents can improve the early diagnosis of IBD and quantitate the severity of inflammation in experimental studies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Luo, Yifan& Gao, Chen& Chen, Wujie& Zhou, Kefeng& Xu, Maosheng. 2020. Molecular Magnetic Resonance Imaging with Contrast Agents for Assessment of Inflammatory Bowel Disease: A Systematic Review. Contrast Media & Molecular Imaging،Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1139253
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Luo, Yifan…[et al.]. Molecular Magnetic Resonance Imaging with Contrast Agents for Assessment of Inflammatory Bowel Disease: A Systematic Review. Contrast Media & Molecular Imaging No. 2020 (2020), pp.1-9.
https://search.emarefa.net/detail/BIM-1139253
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Luo, Yifan& Gao, Chen& Chen, Wujie& Zhou, Kefeng& Xu, Maosheng. Molecular Magnetic Resonance Imaging with Contrast Agents for Assessment of Inflammatory Bowel Disease: A Systematic Review. Contrast Media & Molecular Imaging. 2020. Vol. 2020, no. 2020, pp.1-9.
https://search.emarefa.net/detail/BIM-1139253
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139253
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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