Comparison of Electromechanical Delay during Ventricular Tachycardia and Fibrillation under Different Conductivity Conditions Using Computational Modeling
المؤلفون المشاركون
Heikhmakhtiar, Aulia Khamas
Lim, Ki Moo
المصدر
Computational and Mathematical Methods in Medicine
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-03-29
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Electromechanical delay (EMD) is the time interval between local myocyte depolarization and the onset of myofiber shortening.
Previously, researchers measured EMD during sinus rhythm and ectopic pacing in normal and heart failure conditions.
However, to our knowledge, there are no reports regarding EMD during another type of rhythms or arrhythmia.
The goal of this study was to quantify EMD during sinus rhythm, tachycardia, and ventricular fibrillation conditions.
We hypothesized that EMD under sinus rhythm is longer due to isovolumetric contraction which is imprecise during arrhythmia.
We used a realistic model of 3D electromechanical ventricles.
During sinus rhythm, EMD was measured in the last cycle of cardiac systole under steady conditions.
EMD under tachycardia and fibrillation conditions was measured during the entire simulation, resulting in multiple EMD values.
We assessed EMD for the following 3 conduction velocities (CVs): 31 cm/s, 51 cm/s, and 69 cm/s.
The average EMD during fibrillation condition was the shortest corresponding to 53.45 ms, 55.07 ms, and 50.77 ms, for the CVs of 31 cm/s, 51 cm/s, and 69 cm/s, respectively.
The average EMD during tachycardia was 58.61 ms, 58.33 ms, and 52.50 ms for the three CVs.
Under sinus rhythm with action potential duration restitution (APDR) slope 0.7, the average EMD was 66.35 ms, 66.41 ms, and 66.60 ms in line with the three CVs.
This result supports our hypothesis that EMD under sinus rhythm is longer than that under tachyarrhythmia conditions.
In conclusion, this study observed and quantified EMD under tachycardia and ventricular fibrillation conditions.
This simulation study has widened our understanding of EMD in 3D ventricles under chaotic conditions.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Heikhmakhtiar, Aulia Khamas& Lim, Ki Moo. 2020. Comparison of Electromechanical Delay during Ventricular Tachycardia and Fibrillation under Different Conductivity Conditions Using Computational Modeling. Computational and Mathematical Methods in Medicine،Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1139673
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Heikhmakhtiar, Aulia Khamas& Lim, Ki Moo. Comparison of Electromechanical Delay during Ventricular Tachycardia and Fibrillation under Different Conductivity Conditions Using Computational Modeling. Computational and Mathematical Methods in Medicine No. 2020 (2020), pp.1-10.
https://search.emarefa.net/detail/BIM-1139673
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Heikhmakhtiar, Aulia Khamas& Lim, Ki Moo. Comparison of Electromechanical Delay during Ventricular Tachycardia and Fibrillation under Different Conductivity Conditions Using Computational Modeling. Computational and Mathematical Methods in Medicine. 2020. Vol. 2020, no. 2020, pp.1-10.
https://search.emarefa.net/detail/BIM-1139673
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139673
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر