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Assessment of Drug-Drug Interaction in Ayder Comprehensive Specialized Hospital, Mekelle, Northern Ethiopia: A Retrospective Study
المؤلفون المشاركون
Gebretsadik, Zeru
Gebrehans, Micheale
Getnet, Desalegn
Gebrie, Desye
Alema, Tsgab
Belay, Yared Belete
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-11-08
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Introduction.
Adverse drug interaction is a major cause of morbidity and mortality.
Its occurrence is influenced by a multitude of factors.
The influences of drug-drug interactions (DDIs) can be minimized through creation of awareness to health care professionals.
Objective.
The objective of this study was to assess DDIs in Ayder Comprehensive Specialized Hospital (ACSH).
Methodology.
A retrospective study design was employed on patient prescriptions available in the outpatient department of pharmacy and filled from September 2016 to February 2017 in ACSH.
Result.
From the 600 prescription records assessed, the average number of drugs on single prescription was 2.73.
Regarding the interaction observed 34 (9.63%) prescriptions with major drug-drug interaction, 210 (59.5%) moderate, 87 (24.65%) minor, and 22 (6.22%) unknown were identified.
Age category showed significant association to affect the occurrence of DDIs and polypharmacy had statistically significant association with DDIs in bivariate analysis which was lost in adjusted OR.
Conclusion.
From the current study it can be concluded that nearly half of the prescription ordered in ACSH contained DDIs and from the prescription with interacting medications majority of them had moderate DDIs.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gebretsadik, Zeru& Gebrehans, Micheale& Getnet, Desalegn& Gebrie, Desye& Alema, Tsgab& Belay, Yared Belete. 2017. Assessment of Drug-Drug Interaction in Ayder Comprehensive Specialized Hospital, Mekelle, Northern Ethiopia: A Retrospective Study. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1139725
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gebretsadik, Zeru…[et al.]. Assessment of Drug-Drug Interaction in Ayder Comprehensive Specialized Hospital, Mekelle, Northern Ethiopia: A Retrospective Study. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1139725
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gebretsadik, Zeru& Gebrehans, Micheale& Getnet, Desalegn& Gebrie, Desye& Alema, Tsgab& Belay, Yared Belete. Assessment of Drug-Drug Interaction in Ayder Comprehensive Specialized Hospital, Mekelle, Northern Ethiopia: A Retrospective Study. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1139725
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139725
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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