Long-Term Oncological Outcomes for Young Men Undergoing Radical Prostatectomy for Localized Prostate Cancer
المؤلفون المشاركون
Gudinaviciene, Inga
Venclovas, Zilvinas
Zviniene, Kristina
Matjosaitis, Aivaras Jonas
Milonas, D.
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-02-19
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Aim.
The aim of this study was to describe PCa characteristics and long-term outcomes in young men aged ≤55 years after radical prostatectomy (RP) and to compare them with older men cohort.
Methods.
Among 2,200 patients who underwent RP for clinically localized PCa at our centre between 2001 and 2015, 277 (10.3%) men aged ≤55 years were identified.
All preoperative and pathological parameters were compared between groups.
Biochemical progression free survival (BPFS) and disease progression free survival (DPFS) were assessed at 5 and 10 years.
Results.
Men aged ≤55 years had similar pathological tumor characteristics and biochemical recurrence rate (BCR) compared to their older counterparts.
Disease progression rate 2.5% versus 0.4% was higher in older patients (p=0.026).
BPFS rate was not different in both study groups.
Estimated 10-year DPFS was 98.8% in younger men compared to 89.2% in their older counterparts (p=0.031).
Multivariate Cox regression showed that Gleason score lymph-nodes and surgical margins status were significant predictors for disease progression.
Conclusions.
In our cohort, men aged ≤55 years had similar pathological PCa characteristics and BCR rate in comparison with older men.
RP can be performed with excellent long-term DPFS results in men with localized PCa at ≤55 years of age.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Milonas, D.& Venclovas, Zilvinas& Gudinaviciene, Inga& Zviniene, Kristina& Matjosaitis, Aivaras Jonas. 2017. Long-Term Oncological Outcomes for Young Men Undergoing Radical Prostatectomy for Localized Prostate Cancer. BioMed Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1139744
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Milonas, D.…[et al.]. Long-Term Oncological Outcomes for Young Men Undergoing Radical Prostatectomy for Localized Prostate Cancer. BioMed Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1139744
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Milonas, D.& Venclovas, Zilvinas& Gudinaviciene, Inga& Zviniene, Kristina& Matjosaitis, Aivaras Jonas. Long-Term Oncological Outcomes for Young Men Undergoing Radical Prostatectomy for Localized Prostate Cancer. BioMed Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1139744
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139744
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر