Serum Transthyretin Level as a Plausible Marker for Diagnosis of Child Acute Malnutrition

المؤلفون المشاركون

Tsegaye, Behailu
Mekasha, Amha
Genet, Solomon

المصدر

Biochemistry Research International

العدد

المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2017-08-08

دولة النشر

مصر

عدد الصفحات

6

التخصصات الرئيسية

الكيمياء

الملخص EN

Malnutrition is a major underlying condition for mortality in children under five years of age in developing countries, particularly in Ethiopia.

The most important forms of malnutrition in Ethiopia are protein and energy deficiencies.

There is no reliable laboratory method at present to assess acute malnutrition.

Transthyretin is a homotetrameric serum protein with half-life of two days.

The main objective of this study was to assess the estimation of serum transthyretin level as a useful diagnostic method to evaluate nutritional status of children.

We used a newly designed transthyretin test kit to evaluate nutritional status of children admitted to our hospital.

There is no national reference standard; hence we made a comparative study using anthropometric measurements and measurement of serum albumin level.

A total of 102 children (51 controls and 51 study subjects) were included in this study.

Transthyretin was found to be more sensitive to changes in acute malnutrition than albumin, and its level reflects recent dietary intake compared to overall nutritional status.

The method is more sensitive and reliable for detection of acute malnutrition, along with anthropometric methods.

Measurement of serum transthyretin level can be used as a valuable diagnostic method for assessment of acute malnutrition among children.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Tsegaye, Behailu& Mekasha, Amha& Genet, Solomon. 2017. Serum Transthyretin Level as a Plausible Marker for Diagnosis of Child Acute Malnutrition. Biochemistry Research International،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1139803

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Tsegaye, Behailu…[et al.]. Serum Transthyretin Level as a Plausible Marker for Diagnosis of Child Acute Malnutrition. Biochemistry Research International No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1139803

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Tsegaye, Behailu& Mekasha, Amha& Genet, Solomon. Serum Transthyretin Level as a Plausible Marker for Diagnosis of Child Acute Malnutrition. Biochemistry Research International. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1139803

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1139803