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Melatonin Secretion Pattern in Critically Ill Patients: A Pilot Descriptive Study
المؤلفون المشاركون
Boyko, Yuliya
Holst, René
Jennum, Poul
Oerding, Helle
Nikolic, Miki
Toft, Palle
المصدر
Critical Care Research and Practice
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-05-11
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Critically ill patients have abnormal circadian and sleep homeostasis.
This may be associated with higher morbidity and mortality.
The aims of this pilot study were (1) to describe melatonin secretion in conscious critically ill mechanically ventilated patients and (2) to describe whether melatonin secretion and sleep patterns differed in these patients with and without remifentanil infusion.
Eight patients were included.
Blood-melatonin was taken every 4th hour, and polysomnography was carried out continually during a 48-hour period.
American Academy of Sleep Medicine criteria were used for sleep scoring if sleep patterns were identified; otherwise, Watson’s classification was applied.
As remifentanil was periodically administered during the study, its effect on melatonin and sleep was assessed.
Melatonin secretion in these patients followed a phase-delayed diurnal curve.
We did not observe any effect of remifentanil on melatonin secretion.
We found that the risk of atypical sleep compared to normal sleep was significantly lower (p<0.001) under remifentanil infusion.
Rapid Eye Movement (REM) sleep was only observed during the nonsedation period.
We found preserved diurnal pattern of melatonin secretion in these patients.
Remifentanil did not affect melatonin secretion but was associated with lower risk of atypical sleep pattern.
REM sleep was only registered during the period of nonsedation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Boyko, Yuliya& Holst, René& Jennum, Poul& Oerding, Helle& Nikolic, Miki& Toft, Palle. 2017. Melatonin Secretion Pattern in Critically Ill Patients: A Pilot Descriptive Study. Critical Care Research and Practice،Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1139815
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Boyko, Yuliya…[et al.]. Melatonin Secretion Pattern in Critically Ill Patients: A Pilot Descriptive Study. Critical Care Research and Practice No. 2017 (2017), pp.1-8.
https://search.emarefa.net/detail/BIM-1139815
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Boyko, Yuliya& Holst, René& Jennum, Poul& Oerding, Helle& Nikolic, Miki& Toft, Palle. Melatonin Secretion Pattern in Critically Ill Patients: A Pilot Descriptive Study. Critical Care Research and Practice. 2017. Vol. 2017, no. 2017, pp.1-8.
https://search.emarefa.net/detail/BIM-1139815
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1139815
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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