Incidentally Diagnosed Alport Syndrome in a Patient with Drug-Induced Vasculitis

الملخص EN

A 53-year-old woman is admitted with a serum creatinine of 16 mg/dl.

Seven months earlier, she was diagnosed with heart failure and started on several medications, including Hydralazine.

Laboratory studies revealed the presence of dual Anti-Neutrophil Cytoplasmic Antibodies (anti-MPO and anti-PR3), anti-nuclear and anti-histone antibodies.

The clinical diagnosis was Drug-Induced ANCA Vasculitis (DIAV).

Kidney histology, however, did not reveal crescents, but showed characteristic features of Alport’s syndrome.