Successful Pallidal Deep Brain Stimulation Treatment in a Case of Generalized Dystonia due to a Novel ANO3 Mutation

المؤلفون المشاركون

Lasky, Lizl
Bliss, Lindsay
Sidiropoulos, Christos

المصدر

Case Reports in Neurological Medicine

العدد

المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-2، 2ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2019-11-29

دولة النشر

مصر

عدد الصفحات

2

التخصصات الرئيسية

الطب البشري

الملخص EN

Background.

Dystonia is a ubiquitous syndrome, with a growing number of genes being continually identified.

Mutations in the anoctamin-3 gene have been described to cause dystonia but the management and long-term outcomes are still largely unknown.

Methods.

We present here a long term, longitudinal follow up of a patient with generalized dystonia, who was treated with bilateral pallidal deep brain stimulation and was found to harbor a mutation in the anoctamin-3 gene.

Results.

Ongoing adjustment of stimulation settings and medications led to good and sustained dystonia control; however the patient did suffer short term relapses, manifested as dystonic crisis, which necessitated inpatient admission.

Conclusion.

This only the second patient to be reported with pallidal stimulation and an anoctamin-3 gene mutation.

Long term outcomes seem to be favorable but larger case series are needed to confirm our findings.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Lasky, Lizl& Bliss, Lindsay& Sidiropoulos, Christos. 2019. Successful Pallidal Deep Brain Stimulation Treatment in a Case of Generalized Dystonia due to a Novel ANO3 Mutation. Case Reports in Neurological Medicine،Vol. 2019, no. 2019, pp.1-2.
https://search.emarefa.net/detail/BIM-1141296

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Lasky, Lizl…[et al.]. Successful Pallidal Deep Brain Stimulation Treatment in a Case of Generalized Dystonia due to a Novel ANO3 Mutation. Case Reports in Neurological Medicine No. 2019 (2019), pp.1-2.
https://search.emarefa.net/detail/BIM-1141296

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Lasky, Lizl& Bliss, Lindsay& Sidiropoulos, Christos. Successful Pallidal Deep Brain Stimulation Treatment in a Case of Generalized Dystonia due to a Novel ANO3 Mutation. Case Reports in Neurological Medicine. 2019. Vol. 2019, no. 2019, pp.1-2.
https://search.emarefa.net/detail/BIM-1141296

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1141296