![](/images/graphics-bg.png)
Evaluation of Adrenal Function in Nonhospitalized Patients with Cirrhosis
المؤلفون المشاركون
Moini, Maryam
Yazdani Sarvestani, Mitra
Shams, Mesbah
Nomovi, Masood
المصدر
Canadian Journal of Gastroenterology and Hepatology
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-07-24
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background.
Patients with cirrhosis and advancing hepatic insufficiency may show various degrees of other organ malfunction, including brain, kidney, and lung.
Several studies have also shown a high prevalence of adrenal insufficiency in cirrhotic patients that may cause hemodynamic instability.
Materials and Methods.
In this study we prospectively evaluated adrenal function in a population of nonhospitalized cirrhotic patients.
Categorization of liver disease severity was done according to model for end-stage liver disease (MELD) score.
Adrenocorticotropic hormone stimulation testing was performed on subjects using 250 μg of synthetic short acting hormone; radio immunoassay was used to measure plasma cortisol levels.
Results.
Of 105 cirrhotic patients, 15.23% had evidence of adrenal insufficiency.
These patients were not statistically different from those with normal adrenal function in levels of serum creatinine or bilirubin, MELD score, or presence of cirrhosis related complications.
Significant differences were seen in mean international normalized ratio and serum sodium.
Patients with a sodium level < 135 mEq/L had a higher rate (31.25%) of adrenal insufficiency.
Conclusion.
Adrenal dysfunction was identified in a population of stable nonhospitalized cirrhotic patients.
Our results suggest a possible role for adrenal dysfunction as a contributing factor in hyponatremia in cirrhosis independent of other known factors of neurohormonal activation secondary to systemic vasodilation.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Moini, Maryam& Yazdani Sarvestani, Mitra& Shams, Mesbah& Nomovi, Masood. 2017. Evaluation of Adrenal Function in Nonhospitalized Patients with Cirrhosis. Canadian Journal of Gastroenterology and Hepatology،Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1141357
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Moini, Maryam…[et al.]. Evaluation of Adrenal Function in Nonhospitalized Patients with Cirrhosis. Canadian Journal of Gastroenterology and Hepatology No. 2017 (2017), pp.1-6.
https://search.emarefa.net/detail/BIM-1141357
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Moini, Maryam& Yazdani Sarvestani, Mitra& Shams, Mesbah& Nomovi, Masood. Evaluation of Adrenal Function in Nonhospitalized Patients with Cirrhosis. Canadian Journal of Gastroenterology and Hepatology. 2017. Vol. 2017, no. 2017, pp.1-6.
https://search.emarefa.net/detail/BIM-1141357
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1141357
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
![](/images/ebook-kashef.png)
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
![](/images/kashef-image.png)