Evaluating the Trends of Bloodstream Infections among Pediatric and Adult Patients at a Teaching Hospital of Kathmandu, Nepal: Role of Drug Resistant Pathogens
المؤلفون المشاركون
Parajuli, Narayan Prasad
Khanal, Puspa Raj
Pandit, Roshan
Shakya, Jyotsna
Parajuli, Hridaya
المصدر
Canadian Journal of Infectious Diseases and Medical Microbiology
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-10، 10ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-04-06
دولة النشر
مصر
عدد الصفحات
10
التخصصات الرئيسية
الملخص EN
Bloodstream infections (BSIs) are among the significant causes of morbidity and mortality for patients of all age groups.
However, very little is known about the trends of bacterial bloodstream infections and antimicrobial susceptibilities among pediatric and adult population from Nepal.
In this study, we have investigated the different etiological agents responsible for bloodstream infections among pediatric and adult patients and the role of drug resistant organisms in these infections at a tertiary care teaching hospital of Kathmandu, Nepal.
A total of 3,088 blood culture specimens obtained from pediatric and adult patients suspected to have bloodstream infections were processed by standard microbiological methods.
Significant bacterial pathogens were identified by morphological, biochemical, and serological methods as suggested by American Society for Microbiology.
In vitro antimicrobial susceptibility testing was performed by Kirby-Bauer disk diffusion method and interpreted according to the guidelines of Clinical and Laboratory Standards Institute.
Overall, incidence of bloodstream infections among the suspected patients was 7.48%.
Pediatric patients (n=90, 9.37%) were the significant subgroup of patients affected with bloodstream infections compared to adults (p<0.05, CI-95%).
Gram positive (n=49, 54.4%) bacteria in pediatric and gram negative bacteria (n=141, 78.7%) in adult patients were the most common isolates for BSI.
Staphylococcus aureus (n=41, 45.6%) in pediatric patients and Salmonella enterica (n=40, 28.3%) in adult patients were the leading pathogens.
Trends of antimicrobial resistance among isolated bacterial strains were significantly high in adults compared to pediatric patients.
Methicillin resistant Staphylococcus aureus (MRSA) (31.4%), extended spectrum beta-lactamase (ESBL) (12.5%), and metallo-beta-lactamase (MBL) (3.9%) producing gram negatives were major resistant strains.
Our study shows higher rates of bloodstream infections in pediatric patients compared to adult patients.
Alarming rates of antimicrobial resistance among blood culture isolates is a serious issue.
Prompt and accurate diagnosis and rational antimicrobial therapy are extremely needed.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Parajuli, Narayan Prasad& Parajuli, Hridaya& Pandit, Roshan& Shakya, Jyotsna& Khanal, Puspa Raj. 2017. Evaluating the Trends of Bloodstream Infections among Pediatric and Adult Patients at a Teaching Hospital of Kathmandu, Nepal: Role of Drug Resistant Pathogens. Canadian Journal of Infectious Diseases and Medical Microbiology،Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1141607
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Parajuli, Narayan Prasad…[et al.]. Evaluating the Trends of Bloodstream Infections among Pediatric and Adult Patients at a Teaching Hospital of Kathmandu, Nepal: Role of Drug Resistant Pathogens. Canadian Journal of Infectious Diseases and Medical Microbiology No. 2017 (2017), pp.1-10.
https://search.emarefa.net/detail/BIM-1141607
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Parajuli, Narayan Prasad& Parajuli, Hridaya& Pandit, Roshan& Shakya, Jyotsna& Khanal, Puspa Raj. Evaluating the Trends of Bloodstream Infections among Pediatric and Adult Patients at a Teaching Hospital of Kathmandu, Nepal: Role of Drug Resistant Pathogens. Canadian Journal of Infectious Diseases and Medical Microbiology. 2017. Vol. 2017, no. 2017, pp.1-10.
https://search.emarefa.net/detail/BIM-1141607
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1141607
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر