A Method for Manufacturing Oncological Phantoms for the Quantification of 18F-FDG PET and DW-MRI Studies
المؤلفون المشاركون
D'Ambrosio, Daniela
Gallivanone, F.
Carne, Irene
Interlenghi, Matteo
Baldi, Maurizia
Fantinato, Daniele
Castiglioni, Isabella
المصدر
Contrast Media & Molecular Imaging
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-09-07
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
The aim of this work was to develop a method to manufacture oncological phantoms for quantitation purposes in 18F-FDG PET and DW-MRI studies.
Radioactive and diffusion materials were prepared using a mixture of agarose and sucrose radioactive gels.
T2 relaxation and diffusion properties of gels at different sucrose concentrations were evaluated.
Realistic oncological lesions were created using 3D-printed plastic molds filled with the gel mixture.
Once solidified, gels were extracted from molds and immersed in a low-radioactivity gel simulating normal background tissue.
A breast cancer phantom was manufactured using the proposed method as an exploratory feasibility study, including several realistic oncological configurations in terms of both radioactivity and diffusion.
The phantom was acquired in PET with 18F-FDG, immediately after solidification, and in DW-MRI the following day.
Functional volumes characterizing the simulated BC lesions were segmented from PET and DW-MRI images.
Measured radioactive uptake and ADC values were compared with gold standards.
Phantom preparation was straightforward, and the time schedule was compatible with both PET and MRI measurements.
Lesions appeared on 18F-FDG PET and DW-MRI images as expected, without visible artifacts.
Lesion functional parameters revealed the phantom’s potential for validating quantification methods, in particular for new generation hybrid PET-MRI systems.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gallivanone, F.& Carne, Irene& Interlenghi, Matteo& D'Ambrosio, Daniela& Baldi, Maurizia& Fantinato, Daniele…[et al.]. 2017. A Method for Manufacturing Oncological Phantoms for the Quantification of 18F-FDG PET and DW-MRI Studies. Contrast Media & Molecular Imaging،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1141721
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gallivanone, F.…[et al.]. A Method for Manufacturing Oncological Phantoms for the Quantification of 18F-FDG PET and DW-MRI Studies. Contrast Media & Molecular Imaging No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1141721
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gallivanone, F.& Carne, Irene& Interlenghi, Matteo& D'Ambrosio, Daniela& Baldi, Maurizia& Fantinato, Daniele…[et al.]. A Method for Manufacturing Oncological Phantoms for the Quantification of 18F-FDG PET and DW-MRI Studies. Contrast Media & Molecular Imaging. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1141721
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1141721
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر