Fatal Postpartum Hemorrhage in Diffuse Midline Glioma with H3-K27M Mutation
المؤلفون المشاركون
Hagiwara, Shinya
Miyazaki, Takeshi
Akiyama, Yasuhiko
Tsuji, Masahiro
Minamoto, Toshiko
Ishikawa, Noriyoshi
Hirato, Junko
Nobusawa, Sumihito
المصدر
Case Reports in Obstetrics and Gynecology
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-08-21
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Management of pregnant women with brain tumors necessitates difficult decision-making especially for estimating or preventing its intratumoral hemorrhage.
A 26-year-old, 19-week pregnant woman complaining of headache and vomiting was admitted to our hospital.
Magnetic resonance imaging (MRI) revealed hydrocephalus and a mass lesion without contrast enhancement extending from the left thalamus.
To resolve severe symptoms, a ventriculoperitoneal shunt was inserted, and a biopsy was taken via the right ventricle.
Pathological examination suggested diffuse or pilocytic astrocytoma, but subsequent genetic analysis revealed the diagnosis of midline glioma with H3-K27M mutation.
The patient opted not to terminate the pregnancy, and MRIs conducted every four weeks revealed no change in tumor aspect.
The patient delivered a healthy baby by cesarean section, and postpartum day 1 was uneventful.
However, she was found in a coma due to a massive intratumoral hemorrhage on postpartum day 2 and died 3 weeks after the hemorrhage.
This is the first case report of diffuse midline glioma with H3-K27M mutation in a pregnant woman followed by fatal hemorrhage.
It highlights the necessity of careful clinical management and frequent neuroimaging during the entire perinatal period, even if the tumor has hypovascularity or low proliferative potential on radiological or pathological findings.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Miyazaki, Takeshi& Tsuji, Masahiro& Hagiwara, Shinya& Minamoto, Toshiko& Ishikawa, Noriyoshi& Hirato, Junko…[et al.]. 2019. Fatal Postpartum Hemorrhage in Diffuse Midline Glioma with H3-K27M Mutation. Case Reports in Obstetrics and Gynecology،Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1141764
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Miyazaki, Takeshi…[et al.]. Fatal Postpartum Hemorrhage in Diffuse Midline Glioma with H3-K27M Mutation. Case Reports in Obstetrics and Gynecology No. 2019 (2019), pp.1-5.
https://search.emarefa.net/detail/BIM-1141764
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Miyazaki, Takeshi& Tsuji, Masahiro& Hagiwara, Shinya& Minamoto, Toshiko& Ishikawa, Noriyoshi& Hirato, Junko…[et al.]. Fatal Postpartum Hemorrhage in Diffuse Midline Glioma with H3-K27M Mutation. Case Reports in Obstetrics and Gynecology. 2019. Vol. 2019, no. 2019, pp.1-5.
https://search.emarefa.net/detail/BIM-1141764
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1141764
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر