F-18 FP-CIT PET in Multiple System Atrophy of the Cerebellar Type: Additional Role in Treatment
المؤلفون المشاركون
Jeong, Young Jin
Kang, Do-Young
Cheon, Sang-Myung
Kim, Jae Woo
المصدر
Contrast Media & Molecular Imaging
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-11-29
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
We evaluated the difference in the status of dopamine transporters (DATs) depending on Parkinsonism, cerebellar, and autonomic features using F-18 FP-CIT positron emission tomography (PET) in multiple system atrophy with cerebellar ataxia (MSA-C).
We also assessed whether the DAT PET could be useful in the management of MSA-C.
Forty-nine patients who were clinically diagnosed as possible to probable MSA-C were included.
Based on the F-18 FP-CIT PET results, patients were classified into normal (n=25) and abnormal (n=24) scan groups.
There were statistically significant differences in rigidity, bradykinesia, postural instability, asymmetry, and specific uptake ratio (SUR) between the two groups but no significant differences in tremor and cerebellar/autonomic symptoms.
Dopaminergic medications were administered to 22 patients.
All seven patients with normal scans showed no change, while 10 of the 15 patients with abnormal scans showed clinical improvement.
There was a trend of a negative correlation between levodopa equivalent dose and SUR, but it was not statistically significant.
DAT imaging, such as F-18 FP-CIT PET, may be useful in predicting the response to dopaminergic medication regardless of cerebellar/autonomic symptoms in MSA-C.
In addition to being used for the diagnosis of the disease, it may be used as a treatment decision index.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Jeong, Young Jin& Cheon, Sang-Myung& Kang, Do-Young& Kim, Jae Woo. 2017. F-18 FP-CIT PET in Multiple System Atrophy of the Cerebellar Type: Additional Role in Treatment. Contrast Media & Molecular Imaging،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1141860
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Jeong, Young Jin…[et al.]. F-18 FP-CIT PET in Multiple System Atrophy of the Cerebellar Type: Additional Role in Treatment. Contrast Media & Molecular Imaging No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1141860
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Jeong, Young Jin& Cheon, Sang-Myung& Kang, Do-Young& Kim, Jae Woo. F-18 FP-CIT PET in Multiple System Atrophy of the Cerebellar Type: Additional Role in Treatment. Contrast Media & Molecular Imaging. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1141860
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1141860
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر