A Case Series of Bowen’s Disease Treated with the Combination of Cryosurgery and Ingenol Mebutate and Followed Up with Optical Coherence Tomography
المؤلفون المشاركون
Tsironi, Theodora
Spyridonos, Panagiota
Bassukas, Ioannis D.
Gaitanis, Georgios
المصدر
Case Reports in Dermatological Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-12-16
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Bowen’s disease (BD) is a relatively rare in situ squamous cell carcinoma (SCC) with a limited potential of becoming invasive.
Ingenol mebutate (IM) was relatively successful for the treatment of BD lesions in small case series.
Optical coherence tomography (OCT) is a promising method for the diagnosis of cutaneous keratinocytic carcinomas, including BD.
Herein we report the treatment of BD with the combination of cryosurgery and IM and the application of OCT imagining in treatment monitoring.
Patients treated within a period of 12 months are retrospectively compiled.
Treatment consisted of a mild cryosurgery session (liquid N2, open spray, and 2 freeze-thaw cycles of 15 sec each) of a field including the BD lesion and a 0.5cm rim and IM application for 4 consecutive days starting at the cryosurgery day.
Four patients (3 females; average age: 76.5 years) with 4 lesions (20-70mm maximal diameter; average 36.2mm) were included.
Healing was excellent and no relapse was observed at 12 months’ follow-up.
Baseline OCT revealed a disarranged, thickened epidermis, while a normally layered epidermis overlying a hyperreflective dermis was present after treatment.
Conclusively, the combination of cryosurgery followed by IM is a feasible, effective treatment for BD that should be evaluated in further studies.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Gaitanis, Georgios& Tsironi, Theodora& Spyridonos, Panagiota& Bassukas, Ioannis D.. 2018. A Case Series of Bowen’s Disease Treated with the Combination of Cryosurgery and Ingenol Mebutate and Followed Up with Optical Coherence Tomography. Case Reports in Dermatological Medicine،Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1142862
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Gaitanis, Georgios…[et al.]. A Case Series of Bowen’s Disease Treated with the Combination of Cryosurgery and Ingenol Mebutate and Followed Up with Optical Coherence Tomography. Case Reports in Dermatological Medicine No. 2018 (2018), pp.1-4.
https://search.emarefa.net/detail/BIM-1142862
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Gaitanis, Georgios& Tsironi, Theodora& Spyridonos, Panagiota& Bassukas, Ioannis D.. A Case Series of Bowen’s Disease Treated with the Combination of Cryosurgery and Ingenol Mebutate and Followed Up with Optical Coherence Tomography. Case Reports in Dermatological Medicine. 2018. Vol. 2018, no. 2018, pp.1-4.
https://search.emarefa.net/detail/BIM-1142862
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1142862
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر