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Severe Hyperthyroidism Complicated by Agranulocytosis Treated with Therapeutic Plasma Exchange: Case Report and Review of the Literature
المؤلفون المشاركون
Malhotra, Bharat
Garla, Vishnu
Kovvuru, Karthik
Ahuja, Shradha
Palabindala, Venkatataman
Abdul Salim, Sohail
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-01-10
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Aim.
To present a case of Graves’ disease complicated by methimazole induced agranulocytosis treated with therapeutic plasma exchange (TPE) and review of the literature.
Case Presentation.
A 21-year-old patient with a history of Graves’ disease presented to the endocrine clinic.
His history was significant for heat intolerance, weight loss, and tremors.
Upon examination he had tachycardia, smooth goiter, thyroid bruit, and hyperactive reflexes.
He was started on methimazole and metoprolol and thyroidectomy was to be done once his thyroid function tests normalized.
On follow-up, the patient symptoms persisted.
Complete blood count done showed a white blood cell count of 2100 (4000–11,000 cells/cu mm) with a neutrophil count of 400 cells/cu mm, consistent with neutropenia.
He was admitted to the hospital and underwent 3 cycles of TPE and was also given filgrastim.
He improved clinically and his thyroxine (T4) levels also came down.
Thyroidectomy was done.
He was discharged on levothyroxine for postsurgical hypothyroidism.
Conclusion.
Plasmapheresis may be useful in the treatment of hyperthyroidism.
It works by removing protein bound hormones and also possibly inflammatory cytokines.
Further studies are needed to clarify the role of various modalities of TPE in the treatment of hyperthyroidism.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Garla, Vishnu& Kovvuru, Karthik& Ahuja, Shradha& Palabindala, Venkatataman& Malhotra, Bharat& Abdul Salim, Sohail. 2018. Severe Hyperthyroidism Complicated by Agranulocytosis Treated with Therapeutic Plasma Exchange: Case Report and Review of the Literature. Case Reports in Endocrinology،Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1142960
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Garla, Vishnu…[et al.]. Severe Hyperthyroidism Complicated by Agranulocytosis Treated with Therapeutic Plasma Exchange: Case Report and Review of the Literature. Case Reports in Endocrinology No. 2018 (2018), pp.1-6.
https://search.emarefa.net/detail/BIM-1142960
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Garla, Vishnu& Kovvuru, Karthik& Ahuja, Shradha& Palabindala, Venkatataman& Malhotra, Bharat& Abdul Salim, Sohail. Severe Hyperthyroidism Complicated by Agranulocytosis Treated with Therapeutic Plasma Exchange: Case Report and Review of the Literature. Case Reports in Endocrinology. 2018. Vol. 2018, no. 2018, pp.1-6.
https://search.emarefa.net/detail/BIM-1142960
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1142960
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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