ALK-Negative Anaplastic Large Cell Lymphoma Presenting as Disseminated Intravascular Coagulation and Hemophagocytic Lymphohistiocytosis: A Potentially Fatal Presentation

المؤلفون المشاركون

Ibrahim, Uroosa
Saqib, Amina
Rehan, Maryam
Atallah, Jean Paul

المصدر

Case Reports in Hematology

العدد

المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-3، 3ص.

الناشر

Hindawi Publishing Corporation

تاريخ النشر

2018-04-11

دولة النشر

مصر

عدد الصفحات

3

التخصصات الرئيسية

الأمراض

الملخص EN

Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening disorder that can be familial in etiology or a result of infections, malignancy, and autoimmune or inflammatory disorders.

Disseminated intravascular coagulation (DIC) is common in patients admitted to intensive care units and can confound and delay the diagnosis of HLH.

We present a case of a 69-year-old female who presented with dyspnea and malaise.

Her condition declined rapidly with laboratory parameters consistent with DIC.

In addition, she had a ferritin of 32,522 ng/mL, low haptoglobin, and elevated LDH, and bone marrow biopsy showed hemophagocytic lymphohistiocytes.

She was started on HLH-directed therapy, and later, a diagnosis of ALK-negative anaplastic large cell lymphoma was made on an excisional inguinal lymph node biopsy specimen.

Our case emphasizes the importance of prompt recognition, diagnosis, and treatment of HLH while workup for a primary disorder is still being pursued.

نمط استشهاد جمعية علماء النفس الأمريكية (APA)

Ibrahim, Uroosa& Saqib, Amina& Rehan, Maryam& Atallah, Jean Paul. 2018. ALK-Negative Anaplastic Large Cell Lymphoma Presenting as Disseminated Intravascular Coagulation and Hemophagocytic Lymphohistiocytosis: A Potentially Fatal Presentation. Case Reports in Hematology،Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1143801

نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)

Ibrahim, Uroosa…[et al.]. ALK-Negative Anaplastic Large Cell Lymphoma Presenting as Disseminated Intravascular Coagulation and Hemophagocytic Lymphohistiocytosis: A Potentially Fatal Presentation. Case Reports in Hematology No. 2018 (2018), pp.1-3.
https://search.emarefa.net/detail/BIM-1143801

نمط استشهاد الجمعية الطبية الأمريكية (AMA)

Ibrahim, Uroosa& Saqib, Amina& Rehan, Maryam& Atallah, Jean Paul. ALK-Negative Anaplastic Large Cell Lymphoma Presenting as Disseminated Intravascular Coagulation and Hemophagocytic Lymphohistiocytosis: A Potentially Fatal Presentation. Case Reports in Hematology. 2018. Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1143801

نوع البيانات

مقالات

لغة النص

الإنجليزية

الملاحظات

Includes bibliographical references

رقم السجل

BIM-1143801