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Seronegative Arthritis and Whipple Disease: Risk of Misdiagnosis in the Era of Biologic Agents
المؤلفون المشاركون
Pizzolitto, Stefano
Quartuccio, Luca
Giovannini, Ivan
Scarpa, Maurizio
De Vita, Salvatore
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-10-13
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
We report 2 cases of Whipple disease (WD), previously diagnosed as seronegative polyarthritis and treated for several years with immunosuppressive agents, accordingly.
Both cases had been treated over years with cDMARDs and bDMARDs.
The first patient was a 48-year-old male, who developed a life-threatening disease characterized by fever, significant weight loss, and bloody diarrhoea, supported with RBC transfusions.
The second patient was a 55-year-old man, presenting with arthritis, fever, serositis, lymphadenopathy, thoracic rash, and systemic inflammation; at the beginning he was diagnosed as adult onset Still’s disease.
He was treated with steroids and antitumour necrosis factor agents, but showed no improvement.
Both patients were eventually treated with antimicrobial therapy for WD with dramatic improvement and no clinical relapse in 6 months.
This paper reviews the literature on WD mimicking chronic inflammatory arthritis.
WD may lead to chronic seronegative arthritis that might often be misrecognized.
Importantly, patients treated with bDMARDs and glucocorticoids might develop a life-threatening disease.
Therefore, WD should be suspected and excluded in patients showing resistance or frequent recurrence of chronic arthritis, if seronegative, under treatment with bDMARDs, especially in the presence of new, unexpected sign and/or symptoms.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Quartuccio, Luca& Giovannini, Ivan& Pizzolitto, Stefano& Scarpa, Maurizio& De Vita, Salvatore. 2019. Seronegative Arthritis and Whipple Disease: Risk of Misdiagnosis in the Era of Biologic Agents. Case Reports in Rheumatology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1144213
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Quartuccio, Luca…[et al.]. Seronegative Arthritis and Whipple Disease: Risk of Misdiagnosis in the Era of Biologic Agents. Case Reports in Rheumatology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1144213
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Quartuccio, Luca& Giovannini, Ivan& Pizzolitto, Stefano& Scarpa, Maurizio& De Vita, Salvatore. Seronegative Arthritis and Whipple Disease: Risk of Misdiagnosis in the Era of Biologic Agents. Case Reports in Rheumatology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1144213
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1144213
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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