The Central Nervous System Effects and Mimicry of Common Variable Immunodeficiency (CVID): A Case Report with Literature Review
المؤلفون المشاركون
Figueroa Rodriguez, Fernando
Halalau, Alexandra
Farshad, Sohail
Skender, Joseph
Rasmussen, Cory
Pevzner, Martin
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-09-29
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
There is a scarceness of information on the central nervous system effects of common variable immunodeficiency (CVID).
A 30-year-old woman with a history of recurrent upper respiratory infections, vitiligo, and immune thrombocytopenic purpura presented with right-sided numbness.
Magnetic resonance imaging (MRI) of the thoracic spine revealed a signal hyperintensity.
MRI of the brain demonstrated FLAIR hyperintensity in the right middle frontal gyrus.
Cerebral spinal fluid was unremarkable.
Serum immunoglobulins revealed hypogammaglobulinemia.
Endobronchial and subsequent mediastinum biopsies were all negative for sarcoidosis and malignancy.
No infectious etiology was found.
She was treated with glucocorticoids and intravenous immunoglobulin (IVIG) replacement therapy for CVID-associated myelitis.
Follow-up MRI showed improvement; however, her numbness persisted despite these treatments, which led to an outside physician adding methotrexate for their suspicion of sarcoidosis.
Her symptoms remained stable for two years, but when the methotrexate dose was weaned, her numbness worsened.
Upon review, the treatment team refuted the diagnosis of sarcoidosis but continued treatment with prednisone, IVIG, and methotrexate for CVID-associated myelitis, from which her symptoms have stabilized.
Here, we discuss CVID-associated neurological complications, its similarities to sarcoidosis, and a literature review with treatment regimens and outcomes.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Farshad, Sohail& Figueroa Rodriguez, Fernando& Halalau, Alexandra& Skender, Joseph& Rasmussen, Cory& Pevzner, Martin. 2019. The Central Nervous System Effects and Mimicry of Common Variable Immunodeficiency (CVID): A Case Report with Literature Review. Case Reports in Rheumatology،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1144294
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Farshad, Sohail…[et al.]. The Central Nervous System Effects and Mimicry of Common Variable Immunodeficiency (CVID): A Case Report with Literature Review. Case Reports in Rheumatology No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1144294
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Farshad, Sohail& Figueroa Rodriguez, Fernando& Halalau, Alexandra& Skender, Joseph& Rasmussen, Cory& Pevzner, Martin. The Central Nervous System Effects and Mimicry of Common Variable Immunodeficiency (CVID): A Case Report with Literature Review. Case Reports in Rheumatology. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1144294
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1144294
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر