Omalizumab for Idiopathic Nonhistaminergic Angioedema: Evidence for Efficacy in 2 Patients
المؤلفون المشاركون
Canonica, Giorgio Walter
Brunetta, Enrico
Shiffer, Dana
Folci, Marco
Achenza, Maria I. S.
Puggioni, Francesca
Heffler, Enrico
Furlan, Raffaello
المصدر
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-07-22
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Presently, there is inconclusive evidence regarding the most effective treatment for idiopathic nonhistaminergic acquired angioedema (InH-AAE).
Omalizumab may, however, prove to be a promising option.
This case report describes two patients who presented with recurrent angioedema attacks, which was refractory to antihistamine therapy.
Hence, they were treated with 300 mg omalizumab, every 4 weeks, for a period of 6 months.
Both patients had shown a rapid response to the treatment and achieved complete resolution of symptoms without further AE attacks throughout the entire duration of the treatment period.
After omalizumab’s suspension, one patient remained symptom free for the following 6 months and the other patient had recurrence of symptoms after 2 months for which he was retreated with omalizumab and once again became symptom free.
Although omalizumab seems to be effective as a prophylactic treatment for InH-AAE, the determining factors leading to the differences in time-to-relapse between patients after its suspension remain unclear.
Further studies are needed in order to better determine the potential therapeutic application of omalizumab and its role in maintenance therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Brunetta, Enrico& Shiffer, Dana& Folci, Marco& Achenza, Maria I. S.& Puggioni, Francesca& Heffler, Enrico…[et al.]. 2018. Omalizumab for Idiopathic Nonhistaminergic Angioedema: Evidence for Efficacy in 2 Patients. Case Reports in Immunology،Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1144333
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Brunetta, Enrico…[et al.]. Omalizumab for Idiopathic Nonhistaminergic Angioedema: Evidence for Efficacy in 2 Patients. Case Reports in Immunology No. 2018 (2018), pp.1-3.
https://search.emarefa.net/detail/BIM-1144333
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Brunetta, Enrico& Shiffer, Dana& Folci, Marco& Achenza, Maria I. S.& Puggioni, Francesca& Heffler, Enrico…[et al.]. Omalizumab for Idiopathic Nonhistaminergic Angioedema: Evidence for Efficacy in 2 Patients. Case Reports in Immunology. 2018. Vol. 2018, no. 2018, pp.1-3.
https://search.emarefa.net/detail/BIM-1144333
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1144333
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر