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An Interesting Case of a 57-Year-Old Male with an Upper Gastrointestinal Bleeding and Obstructive Uropathy with Bilateral Hydronephrosis Diagnosed with Systemic Mucormycosis
المؤلفون المشاركون
Izaguirre-Anariba, Dora E.
Chee, Felicia
Thet, Zeyar
Lanza, Jesus
المصدر
Case Reports in Infectious Diseases
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-06-20
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Mucormycosis is a rare and invasive fungal disease with high mortality rate caused by members of the order Mucorales.
Mucorales species are vasotrophic organisms that may cause angioinvasive disease in immunosuppressed hosts.
Risk factors include diabetic ketoacidosis, chronic kidney disease, organ or bone marrow transplantation, neutropenia, burns, malignancies, and steroid therapy.
There are six different clinical presentations of mucormycosis, which includes rhino-orbital cerebral, pulmonary, gastrointestinal, cutaneous, disseminated, and miscellaneous infection.
Here, we report a case of a 57-year-old male with stage-IV sarcoidosis on long-term steroids presenting with upper gastrointestinal bleeding and obstructive uropathy who was diagnosed with systemic mucormycosis.
Biopsy obtained by endoscopy revealed necrotic debris with acute leukocytic exudate and numerous variably sized, 90-degree angulated fungal hyphae favoring mucormycosis-causing species.
Imaging studies showed hydronephrosis, and cystoscopy findings were consistent with fungal infection of the bladder.
Isavuconazonium sulfate was used as systemic salvage therapy along with continuous bladder irrigation with amphotericin-B for localized bladder infection after a trial with first-line systemic treatment with intravenous liposomal amphotericin-B failed.
A repeat endoscopy showed inflammatory changes with a pathology report in which mucormycosis was no longer appreciated.
The patient was discharged home to complete 6 months of antifungal therapy with monthly follow-ups.
The patient has been asymptomatic after 12-month completion of therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Izaguirre-Anariba, Dora E.& Chee, Felicia& Thet, Zeyar& Lanza, Jesus. 2018. An Interesting Case of a 57-Year-Old Male with an Upper Gastrointestinal Bleeding and Obstructive Uropathy with Bilateral Hydronephrosis Diagnosed with Systemic Mucormycosis. Case Reports in Infectious Diseases،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1144595
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Izaguirre-Anariba, Dora E.…[et al.]. An Interesting Case of a 57-Year-Old Male with an Upper Gastrointestinal Bleeding and Obstructive Uropathy with Bilateral Hydronephrosis Diagnosed with Systemic Mucormycosis. Case Reports in Infectious Diseases No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1144595
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Izaguirre-Anariba, Dora E.& Chee, Felicia& Thet, Zeyar& Lanza, Jesus. An Interesting Case of a 57-Year-Old Male with an Upper Gastrointestinal Bleeding and Obstructive Uropathy with Bilateral Hydronephrosis Diagnosed with Systemic Mucormycosis. Case Reports in Infectious Diseases. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1144595
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1144595
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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