Skin Lesions Associated with Nutritional Management of Maple Syrup Urine Disease
المؤلفون المشاركون
Uaariyapanichkul, Jaraspong
Saengpanit, Puthita
Damrongphol, Ponghatai
Suphapeetiporn, Kanya
Chomtho, Sirinuch
المصدر
Case Reports in Dermatological Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-10-25
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Introduction.
Maple syrup urine disease (MSUD) is an inborn error of branched chain amino acids (BCAAs) metabolism.
We report an infant with MSUD who developed 2 episodes of cutaneous lesions as a result of isoleucine deficiency and zinc deficiency, respectively.
Case Presentation.
A 12-day-old male infant was presented with poor milk intake and lethargy.
The diagnosis of MSUD was made based on clinical and biochemical data.
Management and Outcome.
Specific dietary restriction of BCAAs was given.
Subsequently, natural protein was stopped as the patient developed hospital-acquired infections which resulted in an elevation of BCAAs.
Acrodermatitis dysmetabolica developed and was confirmed to be from isoleucine deficiency.
At the age of 6 months, the patient developed severe lethargy and was on natural protein exclusion for an extended period.
Despite enteral supplementation of zinc sulfate, cutaneous manifestations due to zinc deficiency occurred.
Discussion.
Skin lesions in MSUD patients could arise from multiple causes.
Nutritional deficiency including isoleucine and zinc deficiencies can occur and could complicate the treatment course as a result of malabsorption, even while on enteral supplementation.
Parenteral nutrition should be considered and initiated accordingly.
Clinical status, as well as BCAA levels, should be closely monitored in MSUD patients.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Uaariyapanichkul, Jaraspong& Saengpanit, Puthita& Damrongphol, Ponghatai& Suphapeetiporn, Kanya& Chomtho, Sirinuch. 2017. Skin Lesions Associated with Nutritional Management of Maple Syrup Urine Disease. Case Reports in Dermatological Medicine،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1144979
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Uaariyapanichkul, Jaraspong…[et al.]. Skin Lesions Associated with Nutritional Management of Maple Syrup Urine Disease. Case Reports in Dermatological Medicine No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1144979
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Uaariyapanichkul, Jaraspong& Saengpanit, Puthita& Damrongphol, Ponghatai& Suphapeetiporn, Kanya& Chomtho, Sirinuch. Skin Lesions Associated with Nutritional Management of Maple Syrup Urine Disease. Case Reports in Dermatological Medicine. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1144979
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1144979
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر