Diabetes Mellitus Secondary to Acute Pancreatitis in a Child with Wolf-Hirschhorn Syndrome
المؤلف
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-10-24
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Wolf-Hirschhorn Syndrome (WHS) is a rare genetic disease caused by deletion in the short arm of chromosome 4.
It is characterized by typical fascial features and a varying degree of intellectual disabilities and multiple systemic involvement.
Epidemiological studies confirmed the association of acute pancreatitis with the development of diabetes.
However, this association has not been reported in WHS.
We report an 18-year-old girl with WHS who presented acutely with nonketotic Hyperglycemic Hyperosmolar Status (HHS) in association with severe acute pancreatitis.
Her presentation was preceded by febrile illness with preauricular abscess.
She was treated with fluids and insulin infusion and remained on insulin 18 months after presentation.
Her parents are cousins and the mother was diagnosed with type 2 diabetes.
She had negative autoantibodies and no signs of insulin resistance and her monogenic diabetes genetic testing was negative.
Microarray study using WHS probe confirmed deletion of 4p chromosome.
Acute pancreatitis is uncommon in children and development of diabetes following pancreatitis has not been reported in WHS.
HHS is considerably less frequent than diabetes ketoacidosis in children.
We highlight the complex presentation with HHS and acute pancreatitis leading to diabetes that required long term of insulin treatment.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Deeb, Asma. 2017. Diabetes Mellitus Secondary to Acute Pancreatitis in a Child with Wolf-Hirschhorn Syndrome. Case Reports in Endocrinology،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1145075
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Deeb, Asma. Diabetes Mellitus Secondary to Acute Pancreatitis in a Child with Wolf-Hirschhorn Syndrome. Case Reports in Endocrinology No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1145075
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Deeb, Asma. Diabetes Mellitus Secondary to Acute Pancreatitis in a Child with Wolf-Hirschhorn Syndrome. Case Reports in Endocrinology. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1145075
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1145075
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر