False Positive Findings on I-131 WBS and SPECTCT in Patients with History of Thyroid Cancer: Case Series
المؤلفون المشاركون
Kuker, Russ
Hannoush, Zeina C.
Palacios, Juan D.
Casula, Sabina
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-01-26
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
Introduction.
Although whole body scan (WBS) with I-131 is a highly sensitive tool for detecting normal thyroid tissue and metastasis of differentiated thyroid cancer (DTC), it is not specific.
Additional information, provided by single photon emission computed tomography combined with X-ray computed tomography (SPECT/CT) and by the serum thyroglobulin level, is extremely useful for the interpretation of findings.
Case Presentation.
We report four cases of false positive WBS in patients with DTC: ovarian uptake corresponding to an endometrioma, scrotal uptake due to a spermatocele, rib-cage uptake due to an old fracture, and hepatic and renal uptake secondary to a granuloma and simple cyst, respectively.
Conclusions.
Trapping, organification, and storage of iodine are more prominent in thyroid tissue but not specific.
Physiologic sodium-iodine symporter expression in other tissues explains some, but not all, of the WBS false positive cases.
Other proposed etiologies are accumulation of radioiodine in inflamed organs, metabolism of radiodinated thyroid hormone, presence of radioiodine in body fluids, and contamination.
In our cases nonthyroidal pathologies were suspected since the imaging findings were not corroborated by an elevated thyroglobulin level, which is considered a reliable tumor marker for most well-differentiated thyroid cancers.
Clinicians should be aware of the potential pitfalls of WBS in DTC to avoid incorrect management.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Hannoush, Zeina C.& Palacios, Juan D.& Kuker, Russ& Casula, Sabina. 2017. False Positive Findings on I-131 WBS and SPECTCT in Patients with History of Thyroid Cancer: Case Series. Case Reports in Endocrinology،Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1145173
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Hannoush, Zeina C.…[et al.]. False Positive Findings on I-131 WBS and SPECTCT in Patients with History of Thyroid Cancer: Case Series. Case Reports in Endocrinology No. 2017 (2017), pp.1-5.
https://search.emarefa.net/detail/BIM-1145173
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Hannoush, Zeina C.& Palacios, Juan D.& Kuker, Russ& Casula, Sabina. False Positive Findings on I-131 WBS and SPECTCT in Patients with History of Thyroid Cancer: Case Series. Case Reports in Endocrinology. 2017. Vol. 2017, no. 2017, pp.1-5.
https://search.emarefa.net/detail/BIM-1145173
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1145173
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر