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Dasatinib and Prednisolone Induction Therapy for a Case of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia with Dilated Cardiomyopathy Accompanied by Life-Threatening Ventricular Tachycardia
المؤلفون المشاركون
Momose, Dai
Nishimoto, Mitsutaka
Nakamae, Hirohisa
Matsumoto, Kana
Morita, Kunihiko
Koga, Yuki
Hino, Masayuki
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-02-23
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
A 56-year-old man being treated for dilated cardiomyopathy presented with epigastralgia.
He was diagnosed with ventricular tachycardia and Philadelphia chromosome-positive acute lymphoblastic leukemia.
After treating incessant ventricular tachycardia, we commenced induction therapy for leukemia with dasatinib and prednisolone to minimize toxicity towards cardiomyocytes and the cardiac conduction system.
Although dasatinib was temporarily withheld because of a recurrence of ventricular tachycardia, we rechallenged dasatinib while using bisoprolol and amiodarone and achieved a complete hematological response three weeks later.
Although drug interactions between dasatinib and amiodarone were of concern, the blood concentration of each drug remained within the safe range after concomitant use, and there were no adverse cardiac effects such as QT prolongation after rechallenging dasatinib.
Induction therapy with dasatinib and prednisolone may be an acceptable therapeutic option for Philadelphia chromosome-positive acute lymphoblastic leukemia with severe cardiac complications.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nishimoto, Mitsutaka& Nakamae, Hirohisa& Matsumoto, Kana& Morita, Kunihiko& Koga, Yuki& Momose, Dai…[et al.]. 2017. Dasatinib and Prednisolone Induction Therapy for a Case of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia with Dilated Cardiomyopathy Accompanied by Life-Threatening Ventricular Tachycardia. Case Reports in Hematology،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1145853
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nishimoto, Mitsutaka…[et al.]. Dasatinib and Prednisolone Induction Therapy for a Case of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia with Dilated Cardiomyopathy Accompanied by Life-Threatening Ventricular Tachycardia. Case Reports in Hematology No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1145853
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nishimoto, Mitsutaka& Nakamae, Hirohisa& Matsumoto, Kana& Morita, Kunihiko& Koga, Yuki& Momose, Dai…[et al.]. Dasatinib and Prednisolone Induction Therapy for a Case of Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia with Dilated Cardiomyopathy Accompanied by Life-Threatening Ventricular Tachycardia. Case Reports in Hematology. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1145853
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1145853
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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