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Significant Neutrophilic Emperipolesis in Squamous Cell Carcinoma
المؤلفون المشاركون
Emre, Funda
Özsoy, Şule
Bilece, Zeki Tolga
Tas, Faruk
Tetikkurt, Ümit Seza
المصدر
Case Reports in Oncological Medicine
العدد
المجلد 2018، العدد 2018 (31 ديسمبر/كانون الأول 2018)، ص ص. 1-5، 5ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2018-11-13
دولة النشر
مصر
عدد الصفحات
5
التخصصات الرئيسية
الملخص EN
A 53-year-old man was admitted for tooth mobility.
A mass was identified at the tooth base by CT.
Histopathology of the excisional biopsy revealed a moderately differentiated squamous cell carcinoma.
Many intact neutrophils were observed within the malignant cell cytoplasm.
The patient underwent partial maxillectomy and bilateral neck dissection.
Significant neutrophilic emperipolesis was detected in the resected material.
Four tumor recurrences developed in the head and neck region during follow-up.
Surgery and chemoradiotherapy was performed.
The latest tumor recurrence occurred in the peripharyngeal and the posterior parotideal region.
The patient was started on pembrolizumab therapy and nearly complete treatment response occurred.
Pembrolizumab was discontinued due to the adrenal insufficiency and pulmonary tuberculosis that developed as a treatment side effect.
Pembrolizumab was commenced again when tumor recurrence occurred.
The patient is currently alive with ongoing pembrolizumab and antituberculous treatment.
We present this case to remark the presence of a significant neutrophilic emperipolesis in the squamous cell carcinoma of the hard palate and maxilla which is rarely encountered.
Emperipolesis may predict tumor behavior and the consequences of immune-modulating treatment response in squamous cell carcinomas of the head and neck in regard to the findings of our case.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Tetikkurt, Ümit Seza& Tas, Faruk& Emre, Funda& Özsoy, Şule& Bilece, Zeki Tolga. 2018. Significant Neutrophilic Emperipolesis in Squamous Cell Carcinoma. Case Reports in Oncological Medicine،Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1146076
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Tetikkurt, Ümit Seza…[et al.]. Significant Neutrophilic Emperipolesis in Squamous Cell Carcinoma. Case Reports in Oncological Medicine No. 2018 (2018), pp.1-5.
https://search.emarefa.net/detail/BIM-1146076
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Tetikkurt, Ümit Seza& Tas, Faruk& Emre, Funda& Özsoy, Şule& Bilece, Zeki Tolga. Significant Neutrophilic Emperipolesis in Squamous Cell Carcinoma. Case Reports in Oncological Medicine. 2018. Vol. 2018, no. 2018, pp.1-5.
https://search.emarefa.net/detail/BIM-1146076
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1146076
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر
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