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Liver Metastases in Pancreatic Acinar Cell Carcinoma Treated with Selective Internal Radiation Therapy with Y-90 Resin Microspheres
المؤلفون المشاركون
Nasser, Felipe
Motta Leal Filho, Joaquim Maurício
Affonso, Breno Boueri
Galastri, Francisco Leonardo
Cavalcante, Rafael Noronha
Martins, Diego Lima Nava
Segatelli, Vanderlei
Yamaga, Lilian Yuri Itaya
Gansl, Rene Claudio
Tranchesi Junior, Bernardino
Macedo, Antônio Luiz de Vasconcellos
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-7، 7ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-10-11
دولة النشر
مصر
عدد الصفحات
7
التخصصات الرئيسية
الملخص EN
Background.
Pancreatic acinar cell carcinoma (PACC) is a rare tumor.
Surgical resection is the treatment of choice when feasible, but there are no clear recommendations for patients with advanced disease.
Liver-directed therapy with Y-90 selective internal radiation therapy (SIRT) has been used to treat hepatic metastases from pancreatic tumors.
We describe a case of PACC liver metastases treated with SIRT.
Case Report.
59-year-old man was admitted with an infiltrative, solid lesion in pancreatic tail diagnosed as PACC.
Lymph nodes in the hepatic hilum were enlarged, and many metastatic liver nodules were observed.
After partial pancreatectomy, the left and right lobes of the liver were separately treated with Y-90 resin microspheres.
Follow-up imaging revealed that all hepatic nodules shrank by at least 50%, and 3 nodules disappeared completely.
Lipase concentration was 8407 U/L at baseline, rose to 12,705 U/L after pancreatectomy, and declined to 344 U/L after SIRT.
Multiple rounds of chemotherapy in the subsequent year shrank the hepatic tumors further; disease then progressed, but a third line of chemotherapy shrank the tumors again, 16 months after SIRT treatment.
Conclusion.
SIRT had a positive effect on liver metastases from PACC.
In conjunction with systemic therapy, SIRT can achieve sustained disease control.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Nasser, Felipe& Motta Leal Filho, Joaquim Maurício& Affonso, Breno Boueri& Galastri, Francisco Leonardo& Cavalcante, Rafael Noronha& Martins, Diego Lima Nava…[et al.]. 2017. Liver Metastases in Pancreatic Acinar Cell Carcinoma Treated with Selective Internal Radiation Therapy with Y-90 Resin Microspheres. Case Reports in Hepatology،Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1146097
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Nasser, Felipe…[et al.]. Liver Metastases in Pancreatic Acinar Cell Carcinoma Treated with Selective Internal Radiation Therapy with Y-90 Resin Microspheres. Case Reports in Hepatology No. 2017 (2017), pp.1-7.
https://search.emarefa.net/detail/BIM-1146097
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Nasser, Felipe& Motta Leal Filho, Joaquim Maurício& Affonso, Breno Boueri& Galastri, Francisco Leonardo& Cavalcante, Rafael Noronha& Martins, Diego Lima Nava…[et al.]. Liver Metastases in Pancreatic Acinar Cell Carcinoma Treated with Selective Internal Radiation Therapy with Y-90 Resin Microspheres. Case Reports in Hepatology. 2017. Vol. 2017, no. 2017, pp.1-7.
https://search.emarefa.net/detail/BIM-1146097
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1146097
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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