Successful Management of Refractory Type 1 Renal Tubular Acidosis with Amiloride
المؤلفون المشاركون
Chow, Robert D.
Oguejiofor, Patrick
Yim, Kenneth
Jaar, Bernard G.
المصدر
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-01-03
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
A 28-year-old female with history of hypothyroidism, Sjögren’s Syndrome, and Systemic Lupus Erythematosus (SLE) presented with complaints of severe generalized weakness, muscle pain, nausea, vomiting, and anorexia.
Physical examination was unremarkable.
Laboratory test showed hypokalemia at 1.6 mmol/l, nonanion metabolic acidosis with HCO3 of 11 mmol/l, random urine pH of 7.0, and urine anion gap of 8 mmol/l.
CT scan of the abdomen revealed bilateral nephrocalcinosis.
A diagnosis of type 1 RTA likely secondary to Sjögren’s Syndrome was made.
She was started on citric acid potassium citrate with escalating dosages to a maximum dose of 60 mEq daily and potassium chloride over 5 years without significant improvement in serum K+ and HCO3 levels.
She had multiple emergency room visits for persistent muscle pain, generalized weakness, and cardiac arrhythmias.
Citric acid potassium citrate was then replaced with sodium bicarbonate at 15.5 mEq every 6 hours which was continued for 2 years without significant improvement in her symptoms and electrolytes.
Amiloride 5 mg daily was added to her regimen as a potassium sparing treatment with dramatic improvement in her symptoms and electrolyte levels (as shown in the figures).
Amiloride was increased to 10 mg daily and potassium supplementation was discontinued without affecting her electrolytes.
Her sodium bicarbonate was weaned to 7.7 mEq daily.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Oguejiofor, Patrick& Chow, Robert D.& Yim, Kenneth& Jaar, Bernard G.. 2017. Successful Management of Refractory Type 1 Renal Tubular Acidosis with Amiloride. Case Reports in Nephrology،Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1147017
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Oguejiofor, Patrick…[et al.]. Successful Management of Refractory Type 1 Renal Tubular Acidosis with Amiloride. Case Reports in Nephrology No. 2017 (2017), pp.1-3.
https://search.emarefa.net/detail/BIM-1147017
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Oguejiofor, Patrick& Chow, Robert D.& Yim, Kenneth& Jaar, Bernard G.. Successful Management of Refractory Type 1 Renal Tubular Acidosis with Amiloride. Case Reports in Nephrology. 2017. Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1147017
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1147017
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر