Parathyroid Carcinoma in the Setting of Tertiary Hyperparathyroidism: Case Report and Review of the Literature
المؤلفون المشاركون
Cappellacci, Federico
Medas, Fabio
Canu, Gian Luigi
Lai, Maria Letizia
Conzo, Giovanni
Erdas, Enrico
Calò, Pietro Giorgio
المصدر
العدد
المجلد 2020، العدد 2020 (31 ديسمبر/كانون الأول 2020)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2020-12-02
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Introduction.
Parathyroid carcinoma is one of the rarest cancers in normal population, and it is extremely uncommon in the setting of tertiary hyperparathyroidism.
Indeed, only 24 cases have been reported in the literature.
Presentation of the Case.
We report the case of parathyroid carcinoma in a 51-year-old man, with a history of end-stage renal disease due to a horseshoe kidney treated with haemodialysis since 2013.
He came to our attention due to an increase in calcium and parathyroid hormone serum levels.
Neck ultrasound (US) showed a solid hypodense mass, probably the right inferior parathyroid gland, with an estimated size of 25 × 15 × 13 mm; the 99mTc-sestamibi SPECT/CT scan revealed a large radiotracer activity area in the right cervical region, compatible with a hyperfunctioning right inferior parathyroid gland.
So, a tertiary hyperparathyroidism diagnosis was made.
In April 2018, resection of three parathyroid glands was performed.
Histopathological examination demonstrated the right inferior parathyroid gland specimen to be a parathyroid carcinoma, due to the presence of multiple, full-thickness, capsular infiltration foci, and a venous vascular invasion focus.
Discussion.
Diagnosis of parathyroid carcinoma in tertiary hyperparathyroidism is remarkably complex because of the lack of clinical diagnostic criteria and, in many cases, is made postoperatively at histopathological examination.
Conclusion.
To date, radical surgery represents the mainstay of treatment, with a five- and ten-year survival rates overall acceptable.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cappellacci, Federico& Medas, Fabio& Canu, Gian Luigi& Lai, Maria Letizia& Conzo, Giovanni& Erdas, Enrico…[et al.]. 2020. Parathyroid Carcinoma in the Setting of Tertiary Hyperparathyroidism: Case Report and Review of the Literature. Case Reports in Endocrinology،Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1147041
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cappellacci, Federico…[et al.]. Parathyroid Carcinoma in the Setting of Tertiary Hyperparathyroidism: Case Report and Review of the Literature. Case Reports in Endocrinology No. 2020 (2020), pp.1-6.
https://search.emarefa.net/detail/BIM-1147041
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cappellacci, Federico& Medas, Fabio& Canu, Gian Luigi& Lai, Maria Letizia& Conzo, Giovanni& Erdas, Enrico…[et al.]. Parathyroid Carcinoma in the Setting of Tertiary Hyperparathyroidism: Case Report and Review of the Literature. Case Reports in Endocrinology. 2020. Vol. 2020, no. 2020, pp.1-6.
https://search.emarefa.net/detail/BIM-1147041
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1147041
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر