Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting with Fever and Confusion
المؤلفون المشاركون
Liyanage, Chiranthi Kongala
Munasinghe, Tilak Manthi Janake
Paramanantham, Adsareswary
المصدر
Case Reports in Neurological Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-11-06
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis (SREAT) is a diagnostic conundrum as it may present with a myriad of nonspecific clinical features and laboratory and neuroimaging investigations are not diagnostic.
We report a case of a 65-year-old female who presented with an acute febrile illness associated with headache and confusion, tangential thoughts, and loose association.
Based on neutrophil leukocytosis in the full blood count and elevated inflammatory markers, she was commenced on empirical intravenous antibiotics suspecting meningoencephalitis.
Further evaluation found a very high titer of both anti-thyroid peroxidase (anti-TPO) antibodies and anti-thyroid globulin antibodies.
She was clinically and biochemically euthyroid.
EEG showed right sided frontal intermittent rhythmic delta activity (FIRDA).
Cranial MRI revealed age related cerebral atrophy and nonspecific periventricular white matter changes.
A diagnosis of SREAT was made and she was treated with intravenous methylprednisolone followed by oral prednisolone.
Her condition improved dramatically within 48 hours of starting steroids.
SREAT is a diagnosis of exclusion in patients with a central nervous system disorder.
There are no specific clinical features or investigative findings.
Elevated anti-TPO antibodies are considered a hallmark of SREAT and steroid responsiveness supports the diagnosis.
Prompt diagnosis and treatment reverses the neurological dysfunction in most cases.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Liyanage, Chiranthi Kongala& Munasinghe, Tilak Manthi Janake& Paramanantham, Adsareswary. 2017. Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting with Fever and Confusion. Case Reports in Neurological Medicine،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1147129
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Liyanage, Chiranthi Kongala…[et al.]. Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting with Fever and Confusion. Case Reports in Neurological Medicine No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1147129
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Liyanage, Chiranthi Kongala& Munasinghe, Tilak Manthi Janake& Paramanantham, Adsareswary. Steroid-Responsive Encephalopathy Associated with Autoimmune Thyroiditis Presenting with Fever and Confusion. Case Reports in Neurological Medicine. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1147129
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1147129
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر