Primary Angiitis of the Center Nervous System: A Clinical Challenge Diagnosed Postmortem
المؤلفون المشاركون
Al-Share, Bayan
Hiner, Evan
Iskenderian, Ziyad
Warra, Nader
Zakaria, Ali H.
المصدر
Case Reports in Neurological Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-4، 4ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-07-05
دولة النشر
مصر
عدد الصفحات
4
التخصصات الرئيسية
الملخص EN
Primary angiitis of the central nervous system (PACNS) is a rare vasculitis involving medium and small blood vessels of the brain, spinal cord, and meninges, without systemic involvement.
The diffuse and patchy nature of its pathology is reflected by a wide spectrum of nonspecific clinical symptoms.
Diagnosis is challenging due to lack of defined clinical criteria or specific imaging findings.
Specific workup should be done only after exclusion of other etiologies, including infectious, neoplastic, toxic, and other vascular etiologies including systemic vasculitis.
Given the fact that it is a patchy disease with 25% of the biopsies being falsely negative, treating physician should have a high index of suspicion despite negative initial neurovascular imaging and biopsy results.
Once diagnosed, early treatment with immunosuppressive therapy is essential to avoid permanent neurologic damage.
Herein, we are reporting a case of 66-year-old female patient who presented with insidious onset right-sided frontal headache.
Her hospital course progressively worsened and family decision based on her wishes was to refer her to hospice and comfort care.
Despite an extensive workup with advanced imaging techniques, no diagnosis was established until postmortem autopsy and histopathology confirmed primary angiitis of the central nervous system.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Al-Share, Bayan& Zakaria, Ali H.& Hiner, Evan& Iskenderian, Ziyad& Warra, Nader. 2017. Primary Angiitis of the Center Nervous System: A Clinical Challenge Diagnosed Postmortem. Case Reports in Neurological Medicine،Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1147135
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Al-Share, Bayan…[et al.]. Primary Angiitis of the Center Nervous System: A Clinical Challenge Diagnosed Postmortem. Case Reports in Neurological Medicine No. 2017 (2017), pp.1-4.
https://search.emarefa.net/detail/BIM-1147135
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Al-Share, Bayan& Zakaria, Ali H.& Hiner, Evan& Iskenderian, Ziyad& Warra, Nader. Primary Angiitis of the Center Nervous System: A Clinical Challenge Diagnosed Postmortem. Case Reports in Neurological Medicine. 2017. Vol. 2017, no. 2017, pp.1-4.
https://search.emarefa.net/detail/BIM-1147135
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1147135
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر