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Why It Is Not Always Anxiety: A Tough Diagnosis of Stiff Person Syndrome
المؤلفون المشاركون
O’Brien, Keith
Cervantes, Carmen Elena
Lee Lau, Hsien
Binazir, Tina Ataian
Cross, Jonathan S.
المصدر
Case Reports in Neurological Medicine
العدد
المجلد 2017، العدد 2017 (31 ديسمبر/كانون الأول 2017)، ص ص. 1-3، 3ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2017-08-14
دولة النشر
مصر
عدد الصفحات
3
التخصصات الرئيسية
الملخص EN
Anxiety disorder is a commonly used diagnosis that may mask underlying conditions.
Stiff person syndrome (SPS) is a rare neuroimmunological disorder characterized by progressive rigidity and painful muscle spasms affecting axial and lower extremity musculature.
These episodes can be triggered by sudden movement, noise, or emotional stress, which may present as a psychiatric condition.
We report the case of a 30-year-old female who presented with recurrent panic attacks with multiple prior hospital admissions for anxiety, rigidity, and difficulty in walking.
Previous electroencephalogram (EEG) and brain and cervical spine magnetic resonance imaging (MRI) were unremarkable.
She was empirically treated with diazepam and beta-blockers for SPS, which was confirmed by positive glutamic acid decarboxylase (GAD) antibodies.
The patient’s symptoms became refractory to benzodiazepines and required steroids with intravenous immunoglobulin (IVIG).
Her rigidity subsequently responded to plasmapheresis.
In SPS, antibodies in the cerebrospinal fluid (CSF) most commonly target the GAD antigen on gamma-aminobutyric acid (GABA) neurons.
The goal of treatment is to ameliorate symptoms and improve quality of life.
Our case of SPS was masked as generalized anxiety disorder for at least six years since onset of symptoms.
The criteria for both diagnoses may overlap as seen in this patient.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Cervantes, Carmen Elena& Lee Lau, Hsien& Binazir, Tina Ataian& O’Brien, Keith& Cross, Jonathan S.. 2017. Why It Is Not Always Anxiety: A Tough Diagnosis of Stiff Person Syndrome. Case Reports in Neurological Medicine،Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1147202
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Cervantes, Carmen Elena…[et al.]. Why It Is Not Always Anxiety: A Tough Diagnosis of Stiff Person Syndrome. Case Reports in Neurological Medicine No. 2017 (2017), pp.1-3.
https://search.emarefa.net/detail/BIM-1147202
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Cervantes, Carmen Elena& Lee Lau, Hsien& Binazir, Tina Ataian& O’Brien, Keith& Cross, Jonathan S.. Why It Is Not Always Anxiety: A Tough Diagnosis of Stiff Person Syndrome. Case Reports in Neurological Medicine. 2017. Vol. 2017, no. 2017, pp.1-3.
https://search.emarefa.net/detail/BIM-1147202
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1147202
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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