High Level of Serum Tissue Kallikrein Is Associated with Favorable Outcome in Acute Ischemic Stroke Patients
المؤلفون المشاركون
Dong, Qiang
Wu, Fei
Ling, Yifeng
Yang, Lumeng
Cheng, Xin
Cao, Wenjie
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-6، 6ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-06-02
دولة النشر
مصر
عدد الصفحات
6
التخصصات الرئيسية
الملخص EN
Background/Objectives.
We sought to assess the association between a serum tissue kallikrein (TK) level and a 90-day outcome in acute ischemic stroke (AIS) patients who received acute reperfusion therapy.
Methods.
Consecutive AIS patients within 6 hours after stroke onset between December 2015 and August 2017 were prospectively recruited.
Blood samples were collected before acute reperfusion therapy for serum TK measurement.
Outcome was modified Rankin scale (mRS) score at 90 days after stroke onset.
Binary logistic regression was performed to analyze the association between the baseline TK level and the clinical outcome.
Results.
Between December 2015 and August 2017, 75 patients (age range from 33 to 91 years, 72.0% male) were recruited in this study.
Higher baseline TK was independently associated with a favorable functional outcome (mRS 0-2) (odds ratio 1.01, 95% confidence interval (CI) 1.00-1.02, p=0.047) and low mortality rate (odds ratio 0.98, 95% CI 0.96-1.00, p=0.049) at 90 days.
Increased TK level was associated with 90 d mRS (0-2) with area under the curve of 0.719 (95% CI 0.596-0.842; p=0.002).
Conclusions.
Serum TK can be a promising predictor of clinical outcome in AIS patients who received acute reperfusion therapy.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Wu, Fei& Ling, Yifeng& Yang, Lumeng& Cheng, Xin& Dong, Qiang& Cao, Wenjie. 2019. High Level of Serum Tissue Kallikrein Is Associated with Favorable Outcome in Acute Ischemic Stroke Patients. Disease Markers،Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1147359
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Wu, Fei…[et al.]. High Level of Serum Tissue Kallikrein Is Associated with Favorable Outcome in Acute Ischemic Stroke Patients. Disease Markers No. 2019 (2019), pp.1-6.
https://search.emarefa.net/detail/BIM-1147359
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Wu, Fei& Ling, Yifeng& Yang, Lumeng& Cheng, Xin& Dong, Qiang& Cao, Wenjie. High Level of Serum Tissue Kallikrein Is Associated with Favorable Outcome in Acute Ischemic Stroke Patients. Disease Markers. 2019. Vol. 2019, no. 2019, pp.1-6.
https://search.emarefa.net/detail/BIM-1147359
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1147359
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر