Selected Blood Inflammatory and Metabolic Parameters Predicted Successive Bilateral Sudden Sensorineural Hearing Loss
المؤلفون المشاركون
Zheng, Yiqing
Liang, Mao-Jin
Ou, Yongkang
Zhang, Xueyuan
Weng, Yinlun
Xu, Yaodong
Xiong, Hao
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-9، 9ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-07-08
دولة النشر
مصر
عدد الصفحات
9
التخصصات الرئيسية
الملخص EN
Objectives.
To explore whether peripheral inflammatory, metabolic, and hemostatic parameters could predict the pathogenesis of successive bilateral sudden sensorineural hearing loss (SSNHL).
Methods.
This study reviewed 33 patients with successive bilateral SSNHL and 215 patients with unilateral SSNHL.
Clinical characteristics and hematological parameters were compared, including the inflammatory markers (like neutrophil lymphocyte ratio (NLR), monocyte lymphocyte ratio (MLR), and platelet lymphocyte ratio (PLR)) and metabolic features (including hypertension, triglyceridemia, dyslipidemia, and hyperglycemia), as well as hemostatic indices (including prothrombin time (PT), activated partial thromboplastin time (APTT), and fibrinogen).
Results.
In the successive bilateral SSNHL group, older average onset age (48.67±15.36 vs.
42.71±13.58, p<0.05), higher male to female ratio (18 : 15 vs.
112 : 103, p>0.05), and poorer therapeutic efficacy (12% vs.
59%, p<0.01) were observed than those in the unilateral SSNHL group.
Compared to the unilateral SSNHL group, NLR, MLR, and PLR in the successive bilateral SSNHL group were significantly higher (NLR: 5.72±2.23 vs.
4.45±2.82, p=0.01; MLR: 0.25±0.15 vs.
0.17±0.11, p<0.01; PLR: 190.70±69.79 vs.
148.18±65.67; p<0.01); the LDL level was significantly higher; yet, the HDL level was significantly lower (LDL: 3.79±0.53 vs.
3.49±0.74; HDL: 1.33±0.32 vs.
1.44±0.26; p<0.05 for both); fibrinogen was significantly higher (4.03±0.47 vs.
3.70±0.65; p<0.01).
Logistic regression analysis demonstrated that the risk factors for successive bilateral SSNHL included age, NLR, MLR, PLR, LDL, HDL, diabetes, and fibrinogen.
However, only NLR, MLR, PLR, diabetes, LDL, and HDL independently predicted successive bilateral SSNHL.
Conclusion.
Selected blood inflammatory markers combined with metabolic parameters were positively correlated with successive bilateral SSNHL.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Xueyuan& Weng, Yinlun& Xu, Yaodong& Xiong, Hao& Liang, Mao-Jin& Zheng, Yiqing…[et al.]. 2019. Selected Blood Inflammatory and Metabolic Parameters Predicted Successive Bilateral Sudden Sensorineural Hearing Loss. Disease Markers،Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1147678
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Xueyuan…[et al.]. Selected Blood Inflammatory and Metabolic Parameters Predicted Successive Bilateral Sudden Sensorineural Hearing Loss. Disease Markers No. 2019 (2019), pp.1-9.
https://search.emarefa.net/detail/BIM-1147678
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Xueyuan& Weng, Yinlun& Xu, Yaodong& Xiong, Hao& Liang, Mao-Jin& Zheng, Yiqing…[et al.]. Selected Blood Inflammatory and Metabolic Parameters Predicted Successive Bilateral Sudden Sensorineural Hearing Loss. Disease Markers. 2019. Vol. 2019, no. 2019, pp.1-9.
https://search.emarefa.net/detail/BIM-1147678
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1147678
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر