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Proximal Gastrectomy versus Total Gastrectomy for Siewert Type II Adenocarcinoma of the Esophagogastric Junction: A Comprehensive Analysis of Data from the SEER Registry
المؤلفون المشاركون
Zong, Liang
Zhu, Kaixuan
Xu, Yingying
Fu, Jiaxin
Mohamud, Farah Abdidahir
Duan, Zongkui
Tan, Siyuan
Zhao, Zekun
Chen, Ping
المصدر
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-11، 11ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-12-31
دولة النشر
مصر
عدد الصفحات
11
التخصصات الرئيسية
الملخص EN
Background.
To determine the ideal surgical approach (total gastrectomy (TG) vs.
proximal gastrectomy (PG)) for Siewert type II adenocarcinoma of the esophagogastric junction (AEG), we searched and analyzed the Surveillance, Epidemiology, and End Results (SEER) data.
Methods.
Patients with Siewert type II AEG treated by TG or PG were identified from the 2004–2014 SEER dataset.
We obtained the patients’ overall survival (OS) and cancer-specific survival (CSS) and stratified the patients by surgical approach.
We performed a propensity score 1 : 1 matching (PSM) analysis and a univariate and multivariate Cox proportional hazards model.
Results.
A total of 2,217 patients with 6th AJCC stage IA–IIIB Siewert type II AEG was examined: 1,584 patients (71.4%) underwent PG, and 633 patients (28.6%) underwent TG.
The follow-up time was 1–131 months.
OS favored total gastrectomy before the PSM analysis (χ2=3.952, p=0.047), but after this analysis, there was no significant difference between TG and PG (χ2=2.227, p=0.136).
The univariate and multivariate analyses identified age as an independent factor, and an X-tail analysis revealed 70 years as a cut-off point.
The patients aged≥70 years obtained a significant long-term OS benefit from PG compared to TG (χ2=8.245, p=0.004), and those aged<70 years showed no difference between TG and PG (χ2=0.167, p=0.682).
Conclusions.
PG showed an equivalent survival benefit to TG in both the early and locally advanced stages of Siewert type II AEG.
For elderly patients, PG is strongly recommended because of its clearer OS benefit compared to TG.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhu, Kaixuan& Xu, Yingying& Fu, Jiaxin& Mohamud, Farah Abdidahir& Duan, Zongkui& Tan, Siyuan…[et al.]. 2019. Proximal Gastrectomy versus Total Gastrectomy for Siewert Type II Adenocarcinoma of the Esophagogastric Junction: A Comprehensive Analysis of Data from the SEER Registry. Disease Markers،Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1148048
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhu, Kaixuan…[et al.]. Proximal Gastrectomy versus Total Gastrectomy for Siewert Type II Adenocarcinoma of the Esophagogastric Junction: A Comprehensive Analysis of Data from the SEER Registry. Disease Markers No. 2019 (2019), pp.1-11.
https://search.emarefa.net/detail/BIM-1148048
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhu, Kaixuan& Xu, Yingying& Fu, Jiaxin& Mohamud, Farah Abdidahir& Duan, Zongkui& Tan, Siyuan…[et al.]. Proximal Gastrectomy versus Total Gastrectomy for Siewert Type II Adenocarcinoma of the Esophagogastric Junction: A Comprehensive Analysis of Data from the SEER Registry. Disease Markers. 2019. Vol. 2019, no. 2019, pp.1-11.
https://search.emarefa.net/detail/BIM-1148048
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1148048
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
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