The Wound Healing Effect of Callicarpa nudiflora in Scalded Rats
المؤلفون المشاركون
Lai, Weiyong
Zhang, Junqing
Zhang, Xu-guang
Li, Xiu-min
Zhou, Xin-xin
Wang, Yong
Liu, Ying
Luo, Yu-chao
المصدر
Evidence-Based Complementary and Alternative Medicine
العدد
المجلد 2019، العدد 2019 (31 ديسمبر/كانون الأول 2019)، ص ص. 1-8، 8ص.
الناشر
Hindawi Publishing Corporation
تاريخ النشر
2019-05-02
دولة النشر
مصر
عدد الصفحات
8
التخصصات الرئيسية
الملخص EN
Callicarpa nudiflora has been widely used in Li nationality medicine and treated burns and scalds in China.
Our objective was to preliminarily elucidate healing effect and action mechanism of Callicarpa nudiflora water extract (CNE) on the scald wounds using an experimental rat mode.
The second-degree scald wounds were induced by hot water on dorsal surface of Sprague-Dawley (SD) rats, and then they were randomly divided into 5 groups as follows: control (CON), Vaseline, Silver sulfadiazine (SSD), and Vaseline supplemented with 10% and 20% CNE groups.
These ointments were employed locally once daily for 21 days.
The macroscopic analysis showed CNE significantly accelerated the wound healing process and lowered the wound areas on days 15, 18, and 21 especially in 20% CNE group compared to CON group.
Histopathological evaluation showed the mildly hypertrophic epidermis and the intact dermis in the 20% CNE-treated group were obviously distinguished from CON group on day 21.
The CNE-treated groups had no obvious effect for TNF-α and IL-10 expressions on the second day and 14th day, while TGF-β1 expression level was decreased on the 21th day and VEGF level was increased on the 7th day in the 20% CNE group.
Furthermore, the expression level of Samd3 was strongly inhibited in 20% CNE group.
These findings suggested that the CNE can enhance the wound healing and skin repair in deep second-degree scald rats and thus support its traditional use.
نمط استشهاد جمعية علماء النفس الأمريكية (APA)
Zhang, Xu-guang& Li, Xiu-min& Zhou, Xin-xin& Wang, Yong& Lai, Weiyong& Liu, Ying…[et al.]. 2019. The Wound Healing Effect of Callicarpa nudiflora in Scalded Rats. Evidence-Based Complementary and Alternative Medicine،Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1148734
نمط استشهاد الجمعية الأمريكية للغات الحديثة (MLA)
Zhang, Xu-guang…[et al.]. The Wound Healing Effect of Callicarpa nudiflora in Scalded Rats. Evidence-Based Complementary and Alternative Medicine No. 2019 (2019), pp.1-8.
https://search.emarefa.net/detail/BIM-1148734
نمط استشهاد الجمعية الطبية الأمريكية (AMA)
Zhang, Xu-guang& Li, Xiu-min& Zhou, Xin-xin& Wang, Yong& Lai, Weiyong& Liu, Ying…[et al.]. The Wound Healing Effect of Callicarpa nudiflora in Scalded Rats. Evidence-Based Complementary and Alternative Medicine. 2019. Vol. 2019, no. 2019, pp.1-8.
https://search.emarefa.net/detail/BIM-1148734
نوع البيانات
مقالات
لغة النص
الإنجليزية
الملاحظات
Includes bibliographical references
رقم السجل
BIM-1148734
قاعدة معامل التأثير والاستشهادات المرجعية العربي "ارسيف Arcif"
أضخم قاعدة بيانات عربية للاستشهادات المرجعية للمجلات العلمية المحكمة الصادرة في العالم العربي
تقوم هذه الخدمة بالتحقق من التشابه أو الانتحال في الأبحاث والمقالات العلمية والأطروحات الجامعية والكتب والأبحاث باللغة العربية، وتحديد درجة التشابه أو أصالة الأعمال البحثية وحماية ملكيتها الفكرية. تعرف اكثر